Sodium Hyaluronate Injection

What is this medication?

SODIUM HYALURONATE (SOE dee um hye al yoor ON ate) treats arthritis of the knee. It works by acting like a lubricant and cushion in the joint. This helps the joint move easily, which reduces pain.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Amvisc, DUROLANE, Euflexxa, GELSYN-3, Hyalgan, Hymovis, Monovisc, Orthovisc, Supartz, Supartz FX, SynoJoynt, Triluron, TriVisc, VISCO

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Bleeding problems
• Infection in or around the knee
• Skin conditions around the knee
• Swelling around the knee
• An unusual allergic reaction to sodium hyaluronate, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breastfeeding

How should I use this medication?

This medication is injected into the knee joint. It is given by your care team in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medication?

Interactions are not expected.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.

Talk to your care team about how active you should be after treatment. Avoid movement and exercise that take a lot of effort for 48 hours after treatment. This means no running, jogging, or tennis for at least 2 days. Also, avoid putting weight on the joint for more than an hour at a time during this time period.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

• Headache
• Pain, redness, or irritation at injection site
• Swelling in the joint where injected
• Nausea

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.