Rotigotine Transdermal Skin Patch

What is this medication?

ROTIGOTINE (roe TIG oh teen) is used to treat symptoms of Parkinson's disease. It can also be used to treat restless legs syndrome.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Neupro

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• heart disease
• high blood pressure
• low blood pressure
• kidney disease
• mental illness
• narcolepsy
• sleep apnea
• an unusual or allergic reaction to rotigotine, sulfites, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medication?

This medicine is for external use only. Use it as directed on the prescription label. Change the patch each day at the same time. Always remove the old patch before you apply a new one. Wash hands after removing and applying this medicine. Keep using it unless your health care provider tells you to stop.

This medicine comes with INSTRUCTIONS FOR USE. Ask your pharmacist for directions on how to use this medicine. Read the information carefully. Talk to your pharmacist or health care provider if you have questions.

Talk to your health care provider about the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

• alcohol
• antihistamines for allergy, cough and cold
• certain medicines for sleep
• medicines for depression, anxiety, or psychotic disturbances
• metoclopramide
• narcotic medicines for pain

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your health care provider for regular checks on your progress. Tell your health care provider if your symptoms do not start to get better or if they get worse.

Do not suddenly stop taking this medicine. You may develop a severe reaction. Your health care provider will tell you how much medicine to take. If your health care provider wants you to stop the medicine, the dose may be slowly lowered over time to avoid any side effects.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

When taking this medicine, you may fall asleep without notice. You may be doing activities like driving a car, talking, or eating. You may not feel drowsy before it happens. Contact your health care provider right away if this happens to you.

There have been reports of increased sexual urges or other strong urges such as gambling while taking this medicine. If you experience any of these while taking this medicine, you should report this to your health care provider as soon as possible.

This medicine patch is sensitive to certain body heat changes. If your skin gets too hot, more medicine will come out of the patch. Call your health care provider if you get a fever. Do not take hot baths. Do not sunbathe. Do not use hot tubs, saunas, hairdryers, heating pads, electric blankets, heated waterbeds, or tanning lamps. Do not do exercise that increases your body temperature.

If you are going to have a magnetic resonance imaging (MRI) procedure, tell your MRI technician if you have this patch on your body. It must be removed before an MRI.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• changes in emotions or moods
• confusion
• depressed mood
• dizziness
• falling asleep during normal activities like driving
• fast, irregular, or slow heartbeat
• feeling faint or lightheaded, falls
• hallucinations
• new or increased gambling urges, sexual urges, uncontrolled spending, binge or compulsive eating, or other urges
• skin irritation, redness, or swelling
• trouble breathing
• uncontrollable movements of the arms, face, head, mouth, neck, or upper body

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• constipation
• headache
• loss of appetite
• nausea
• trouble sleeping
• weight gain

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Store in original pouch until just before use. Get rid of any unused medicine after the expiration date.

To get rid of medicines that are no longer needed or have expired:

• Take the medicine to a medicine take-back program. Check with your pharmacy or law enforcement to find a location.
• If you cannot return the medicine, ask your pharmacist or health care provider how to get rid of this medicine safely.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.