Sevoflurane

What is this medication?

SEVOFLURANE is a medicine that you breathe to help reduce any pain from a procedure or surgery.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Ultane

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

•a history of malignant hyperthermia

•kidney disease

•liver disease

•neuromuscular disease like Duchenne muscular dystrophy

•seizures

•an unusual or allergic reaction to sevoflurane, other medicines, foods, dyes, or preservatives

•pregnant or trying to get pregnant

•breast-feeding

How should I use this medication?

This medication is for inhalation. It is given by your care team in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as neonates for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply. This medication is not for regular use.

What may interact with this medication?

Do not take this medicine with any of the following medications:

• astemizole
• bepridil
• certain antibiotics like grepafloxacin and sparfloxacin
• cisapride
• droperidol
• halofantrine
• levomethadyl
• MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
• phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
• pimozide
• St. John's wort
• terfenadine

This medicine may also interact with the following medications:

• alcohol
• isoniazid, INH
• narcotic medicines for pain
• neuromuscular blockers like pancuronium, vecuronium, and atracurium
• ziprasidone

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medication.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medication. Avoid alcoholic drinks.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

•allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

•breathing problems

•dark urine

•fast, irregular heartbeat

•feeling faint or lightheaded, falls

•general ill feeling or flu-like symptoms

•high body temperature

•right upper belly pain

•seizures

•slow or difficult breathing

•unusually weak or tired

•yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

•agitation, nervousness

•cough

•drowsiness

•nausea, vomiting

•shivering

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.