What is this medication?

CEFTRIAXONE (sef try AX one) treats infections caused by bacteria. It belongs to a group of medications called cephalosporin antibiotics. It will not treat colds, the flu, or infections caused by viruses.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Ceftrisol Plus, Rocephin

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Bleeding disorder
  • High bilirubin level in newborn patients
  • Kidney disease
  • Liver disease
  • Poor nutrition
  • An unusual or allergic reaction to ceftriaxone, other penicillin or cephalosporin antibiotics, other medicines, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

How should I use this medication?

This medication is injected into a vein or into a muscle. It is usually given by a health care provider in a hospital or clinic setting. It may also be given at home.

If you get this medication at home, you will be taught how to prepare and give it. Use exactly as directed. Take it as directed on the prescription label at the same time every day. Take all of this medication unless your care team tells you to stop it early. Keep taking it even if you think you are better.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your care team to get one.

Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as newborns for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you get this medication at the hospital or clinic: It is important not to miss your dose. Call your care team if you are unable to keep an appointment.

If you give yourself this medication at home: If you miss a dose, take it as soon as you can. Then continue your normal schedule. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. Call your care team with questions.

What may interact with this medication?

  • Birth control pills
  • Intravenous calcium

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Tell your care team if your symptoms do not start to get better or if they get worse.

Do not treat diarrhea with over the counter products. Contact your care team if you have diarrhea that lasts more than 2 days or if it is severe and watery.

If you have diabetes, you may get a false-positive result for sugar in your urine. Check with your care team.

If you are being treated for a sexually transmitted disease (STD), avoid sexual contact until you have finished your treatment. Your sexual partner may also need treatment.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Confusion
  • Drowsiness
  • Gallbladder problems—severe stomach pain, nausea, vomiting, fever
  • Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
  • Kidney stones—blood in the urine, pain or trouble passing urine, pain in the lower back or sides
  • Low red blood cell count—unusual weakness or fatigue, dizziness, headache, trouble breathing
  • Pancreatitis—severe stomach pain that spreads to your back or gets worse after eating or when touched, fever, nausea, vomiting
  • Seizures
  • Severe diarrhea, fever
  • Unusual weakness or fatigue

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Diarrhea

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

You will be instructed on how to store this medication. Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

  • Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
  • If you cannot return the medication, ask your care team how to get rid of this medication safely.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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