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Gadoxetate Disodium Injection

What is this medication?

GADOXETATE DISODIUM (gad OX e tate dye SO dee um) helps find or diagnose problems with blood vessels, organs, or other tissues in the body. It works by making parts of the body easier to view during imaging scans, such as CT, MRI, or X-ray. It belongs to a group of medications called contrast agents.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Eovist

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Asthma
  • Diabetes
  • High blood pressure
  • History of blood diseases, such as sickle cell anemia
  • Kidney disease
  • Previous MRI with contrast or dye
  • An unusual or allergic reaction to gadoxetate disodium, contrast agents, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breastfeeding

How should I use this medication?

This medication is injected into a vein. It is given by your care team in a hospital or clinic setting.

A special MedGuide will be given to you by your care team. Be sure to read this information carefully.

Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 3 months for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medication?

Interactions are not expected.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medicine.

This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Burning, itching, hardening, or thickening of the skin, red or dark patches on the skin, joint stiffness or pain
  • Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Change in taste
  • Dizziness
  • Headache
  • Nausea
  • Pain, redness, or irritation at injection site

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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