Colesevelam is a medication that lowers cholesterol if you’re at a high risk of heart disease or stroke. Cholesterol is a type of fat that helps your body perform many important functions. Too much cholesterol in your blood is bad for your health.
COLESEVELAM (koh le SEV e lam) treats high cholesterol. It works by removing bile acid from your body and decreasing the amount of bad cholesterol (such as LDL) in your blood. It may also be used to treat type 2 diabetes. It works by decreasing your blood sugar (glucose). Changes to diet and exercise are often combined with this medication.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): WelChol
They need to know if you have any of these conditions:
Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. Take it with food. Keep taking it unless your care team tells you to stop.
This medication contains colesevelam hydrochloride. It should be taken at a different time of day than some other medications taken by mouth. Talk to your care team if you are not sure if you should separate the timing of your drugs.
Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 10 for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
You may need blood work while you are taking this medication.
This medication may cause constipation. If you do not have a bowel movement for 3 days, call your care team.
Taking this medication is only part of a total heart healthy program. Your care team may give you a special diet to follow. Avoid alcohol. Avoid smoking. Ask your care team how much you should exercise.
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children and pets.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
Copyright ©2023 Elsevier Inc. All Rights Reserved.
Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.