Neomycin; Polymyxin B; Gramicidin Eye Solution

What is this medication?

NEOMYCIN; POLYMYXIN B; GRAMICIDIN (nee oh MYE sin; pol i MIX in B; gram i SYE din) is an antibiotic. It is used in the eye to treat certain types of infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): AK-Spore, AK-Spore Ophthalmic, Neocidin, Neosporin, Neosporin Ophthalmic Solution, Ocu-Spore-G, Polymycin

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What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • an unusual or allergic reaction to neomycin, polymyxin b, gramicidin, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medication?

This medicine is only for use in the eye. Do not take by mouth. Follow the directions on the prescription label. Wash hands before and after use. Tilt your head back slightly and pull your lower eyelid down with your index finger to form a pouch. Try not to touch the tip of the dropper to your eye, fingertips, or any other surface. Squeeze the prescribed number of drops into the pouch. Close the eye gently to spread the drops. Your vision may blur for a few minutes. Use your doses at regular intervals. Do not use your medicine more often than directed. Finish the full course prescribed by your doctor or health care professional even if you think your condition is better.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

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What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medication?

Interactions are not expected. Do not use any other eye products without telling your doctor or health care professional.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse.

If your eyes are more sensitive to light, wear sunglasses.

Do not wear contact lenses while you have any signs or symptoms of an eye infection. Ask your doctor or health care professional when you can start wearing your lenses again.

Stop using this medicine immediately if you notice signs of an allergic reaction.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • blurred vision that does not go away
  • burning, stinging, or itching of the eyes or eyelids
  • redness, swelling, or pain of the eyes or eyelids

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • temporary blurred vision
  • tearing or feeling of something in the eye

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Protect from light. Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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