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Clindamycin Vaginal Cream

Clindamycin cream treats bacterial infections in your vagina. You can apply this antibiotic cream using the applicator that comes with this medication. Make sure you wash your hands before and after using this medication.

What is this medication?

CLINDAMYCIN (KLIN da MYE sin) treats infections caused by too much bacteria in the vagina. It belongs to a group of medications called antibiotics. It will not treat yeast infections or infections caused by viruses.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Cleocin, ClindaMax, Clindesse

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Stomach or intestine problems, such as colitis
  • An unusual or allergic reaction to clindamycin, other medications, foods, dyes or preservatives
  • Pregnant or trying to get pregnant
  • Breastfeeding

How should I use this medication?

This medication is only for use in the vagina. Do not take by mouth. Wash your hands before and after use. Do not get it in your eyes. If you do, rinse your eyes with plenty of cool tap water. Use it as directed on the prescription label. Do not use it more often than directed. Use the medication for the full course as directed by your care team, even if you think you are better. Do not stop using it unless your care team tells you to stop it early.

Place the medication in the vagina using the special applicator supplied with the cream. Fill the applicator with cream. Lie on your back, part and bend your knees. Gently insert the applicator into the vagina and push the plunger to place the cream into the vagina.

This medication comes with INSTRUCTIONS FOR USE. Ask your pharmacist for directions on how to use this medication. Read the information carefully. Talk to your pharmacist or care team if you have questions.

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Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medication?

Interactions are not expected. Do not use any other vaginal products without telling your care team.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Tell your care team if your symptoms do not start to get better or if they get worse.

Do not have sex or use vaginal products, such as tampons or douches, while using this medication and for a time after use. Having sex or using vaginal products can make this medication not work as well. Talk with your care team about how long to not have sex or use vaginal products after the last dose.

This medication can damage and reduce the effect of latex-containing products, such as condoms and diaphragms. Avoid use of latex-containing products while taking this medication and for 3 days after the last dose. Get rid of any latex-containing products that are exposed to this medication.

Your clothing may get soiled. To help prevent reinfection, wear freshly washed cotton, not synthetic, underwear.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Severe diarrhea, fever
  • Unusual vaginal discharge, itching, or odor

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Vaginal irritation at application site

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date. Do not freeze.

To get rid of medications that are no longer needed or have expired:

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  • Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
  • If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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