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Carmustine, BCNU implant wafers

What is this medication?

CARMUSTINE, BCNU (kar MUS teen) is a chemotherapy drug. It interferes with the growth of rapidly growing cells like cancer cells. This medicine is used to treat glioma and glioblastoma. The wafers are placed at a site where a brain tumor used to be, at the end of a surgery to remove the tumor.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Gliadel

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • seizures
  • an unusual or allergic reaction to carmustine, BCNU, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medication?

This drug is placed into the space made when a tumor is removed. It is administered during surgery in a hospital.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medication?

Interactions are not expected.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your doctor for checks on your progress. You will need to have regular blood work. Report any side effects.

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This may interfere with the ability to father a child. You should talk to your doctor or health care professional if you are concerned about your fertility.

Do not become pregnant for 6 months after this medicine is administered. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child for 3 months after this medicine is administered. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant for at least 7 days after this medicine is administered.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • changes in vision
  • fever
  • nausea, vomiting
  • seizures
  • severe headache
  • stiff neck and sensitivity to light

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • changes in emotions or moods
  • constipation
  • weakness

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This drug is given in a hospital and will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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