Methenamine; Sodium Phosphate; Methylene Blue; Hyoscyamine Tablets

What is this medication?

METHENAMINE; SODIUM PHOSPHATE; METHYLENE BLUE; HYOSCYAMINE (meth EN a meen; SOE dee um FOS fate; METH uh leen bloo; hye oh SYE a meen) relieves symptoms caused by irritation of the urinary tract, such as pain, burning, and passing frequent small amounts of urine. It works by relaxing the muscles of the bladder, which decreases spasms. It is not an antibiotic. It will not treat a urinary tract infection (UTI).

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Indiomin MB, Uro-BLUE, Urogesic Blue, Urolet, UTA

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Bladder or prostate problems or trouble passing urine
• Dehydration
• Glaucoma
• Heart disease
• High blood pressure
• High levels of phosphate in the blood
• High levels of sodium in the blood
• Kidney disease
• Liver disease
• Myasthenia gravis
• Sodium (salt) restricted diet
• Stomach problems
• An unusual or allergic reaction to methenamine, sodium acid phosphate, methylene blue, hyoscyamine, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

How should I use this medication?

Take this medication by mouth with a glass of water. Take it as directed on the prescription label. Take all this medication unless your care team tells you to stop it early. Keep taking it even if you think you are better.

Talk to your care team about the use of this medication in children. While it may be prescribed for children at young as 6 years, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

This medication may interact with the following:

• Antacids
• Antihistamines for allergy, cough and cold
• Atropine
• Certain antibiotics, such as sulfacetamide, sulfamethoxazole
• Certain medications for bladder problems, such as oxybutynin, tolterodine
• Certain medications for blood pressure, such as hydrochlorothiazide
• Certain medications for depression, anxiety, or mental health conditions
• Certain medications for Parkinson disease, such as benztropine, trihexyphenidyl
• Certain medications for stomach problems, such as dicyclomine, hyoscyamine
• Certain medications for travel sickness, such as scopolamine
• Ipratropium
• Ketoconazole
• MAOIs, such as Carbex, Eldepryl, Marplan, Nardil, and Parnate
• Opioid medications for pain

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Tell your care team if your symptoms do not start to get better or if they get worse.

This medication may affect your coordination, reaction time, or judgement. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your care team if the problem does not go away or is severe.

You may need to be on a special diet while taking this medication. Ask your care team how many glasses of fluids you need to drink each day. Also, ask which foods to include and which to avoid to help keep your urine acidic. Your urine must be acidic for this medication to work.

This medication may cause dry eyes and blurred vision. If you wear contact lenses, you may feel some discomfort. Lubricating drops may help. See your eye care team if the problem does not go away or is severe.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

• Blue or blue-green urine or stools
• Blurry vision
• Dizziness
• Dry mouth
• Nausea
• Upset stomach

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

• Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
• If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.