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Ephedrine Injection

What is this medication?

EPHEDRINE (e FED rin) is used to treat low blood pressure in patients who receive anesthesia during surgery.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): AKOVAZ, CORPHEDRA, Placidyl, REZIPRES

What should I tell my care team before I take this medication?

They need to know if you have any of the following conditions:

  • diabetes (high blood sugar)
  • glaucoma
  • heart disease
  • high blood pressure
  • high thyroid levels
  • irregular heartbeat or rhythm
  • an unusual or allergic reaction to ephedrine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medication?

This medicine is injected into a vein. It is given by a health care provider in a hospital or clinic setting.

Talk to your health care provider about the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply. This medicine is not for regular use.

What may interact with this medication?

  • atropine
  • certain medicines for blood pressure, heart disease, irregular heart beat
  • clonidine
  • digoxin
  • MAOIs like Marplan, Nardil, and Parnate
  • methylergonovine
  • oxytocin
  • propofol
  • rocuronium
  • theophylline

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medicine.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions (skin rash, itching or hives; swelling of the face, lips, or tongue)
  • heartbeat rhythm changes (trouble breathing; chest pain; dizziness; fast, irregular heartbeat; feeling faint or lightheaded, falls)

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • dizziness
  • nausea, vomiting
  • restlessness

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medicine is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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