Orlistat is a medication that can help you lose weight or maintain weight loss by decreasing the amount of fat that your body absorbs from the food you eat. A healthcare provider will recommend a reduced-calorie diet when taking this medication. You can take this medication with a glass of water during meals.
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ORLISTAT (OR li stat) promotes weight loss. It may also be used to maintain weight loss. It works by decreasing the amount of fat your body absorbs from food. Changes to diet and exercise are often combined with this medication.
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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): alli, Xenical
They need to know if you have any of these conditions:
Take this medication by mouth with a glass of water. Follow the directions on the prescription or product label. Take this medication with each main meal that contains about 30 percent of the calories from fat or within 1 hour after each meal. Do not take your medication more often than directed. If you occasionally miss a meal or have a meal without fat, you can skip that dose of this medication.
Talk to your care team about the use of this medication in children. Special care may be needed. While this medication may be prescribed for children as young as 12 years for selected conditions, precautions do apply. Use of this medication without a prescription is not approved in children less than 18 years.
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Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, take it within 1 hour following the meal that contains fat. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. If you occasionally miss a meal or have a meal without fat, you can skip that dose of this medication.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your care team for regular checks on your progress.
This medication can cause decreased absorption of some vitamins. You should take a daily multivitamin that contains normal amounts of vitamins D, E, K and beta-carotene or vitamin A. Take the multivitamin once per day at bedtime unless otherwise directed by your care team. Discuss the foods you eat and the vitamins you take with your care team.
You should use this medication with a reduced-calorie diet that contains no more than about 30 percent of the calories from fat. Divide your daily intake of fat, carbohydrates, and protein evenly over your 3 main meals. Follow a well-balanced, reduced-calorie, low fat diet. Try starting this diet before taking this medication. Following a low fat diet can help reduce the possible side effects from this medication.
Tell your care team if you wish to become pregnant or think you might be pregnant. Losing weight while pregnant is not advised and may cause harm to the unborn child. Talk to your care team for more information.
Do not use this medication if you have had an organ transplant. This medication interferes with some medications used to prevent transplant rejection.
Side effects that you should report to your care team as soon as possible:
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Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children and pets.
Storage at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep container tightly closed. Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.