What is this medicine?
PSEUDOEPHEDRINE; TRIPROLIDINE (soo doe e FED rin; trye PROE li deen) is a combination of an antihistamine and a decongestant. It is used to treat the symptoms of allergy and colds. This medicine will not treat an infection.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Actifed Cold and Allergy, Allerfrim, Aprodine, ED A-HIST, Genac, Histafed, Sudafed Sinus Nighttime, Tri-Sudo
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
- difficulty passing urine
- heart disease
- high blood pressure
- lung or breathing disease, like asthma
- taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
- thyroid disease
- ulcer or other stomach problem
- an unusual or allergic reaction to pseudoephedrine, triprolidine, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take it more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years for selected conditions, precautions do apply.
Patients over 65 years old may have a stronger reaction and need a smaller dose.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
- MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
This medicine may also interact with the following medications:
- any stimulant drug
- certain medicines for stomach problems like dicyclomine, hyoscyamine
- certain medicines for travel sickness like scopolamine
- certain medicines for Parkinson's disease like benztropine, trihexyphenidyl
- medicines for chest pain, heart disease, high blood pressure or heart rhythm problems
- medicines for depression, anxiety, or psychotic disturbances
- medicines for sleep
- narcotic medicines for pain
- other decongestants, like pseudoephedrine
- other medicines for allergy, cough, cold
- some herbal or nutritional supplements
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Tell your doctor or health care professional if your symptoms do not improve or if they get worse. If you have trouble falling asleep at night, take the last dose of the day at least a few hours before bedtime.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
This medicine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye doctor if the problem does not go away or is severe.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- breathing problems
- changes in vision
- fast or irregular heartbeat
- feeling faint or lightheaded, falls
- high blood pressure
- trouble passing urine or change in the amount of urine
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
- loss of appetite
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.