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Miconazole Buccal Tablets

What is this medication?

MICONAZOLE (mi KON a zole) treats thrush, a fungal or yeast infection in the mouth. It belongs to a group of medications called antifungals. It will not treat colds, the flu, or infections caused by bacteria or viruses.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Oravig

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Liver disease
  • An unusual or allergic reaction to miconazole, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

How should I use this medication?

With dry hands, apply the round side of the medication to your upper gum, to the right or left of your two front teeth. Hold the tablet in place using slight pressure to the outer lip for 30 seconds to help the tablet stick to the gum. Follow the directions on the prescription label. Do not cut, crush, or chew this medication. You may eat and drink while using this medication, but do not chew gum. Change where you place this medication between the right and left side of your upper gum with each use. If this medication does not stick or falls off within the first 6 hours, reapply it. If it still does not stick, replace it with a new tablet. If you swallow the tablet within the first 6 hours, drink a glass of water and apply a new tablet only once. If this medication falls off or is swallowed after it was in place for 6 hours, do not apply a new tablet. Place your next dose at the regular time. Upper dentures may interfere with the placement of this medication. Take all of this medication unless your care team tells you to stop it early. Keep taking it even if you think you are better.

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Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, apply it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medication?

  • Certain medications for diabetes
  • Certain medications that treat or prevent blood clots, such as warfarin
  • Ergot alkaloids, such as dihydroergotamine, ergonovine, ergotamine, methylergonovine
  • Phenytoin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Tell your care team if your symptoms do not start to get better or if they get worse.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Cough
  • Diarrhea
  • Dry mouth
  • Headache
  • Irritation inside the mouth or throat
  • Nausea
  • Stomach pain

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture. Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

  • Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
  • If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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