Dasatinib treats chronic myeloid leukemia and acute lymphoblastic leukemia. Leukemia is a cancer that affects your blood-producing cells. You can take this tablet by mouth with a glass of water as directed.
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DASATINIB (da SA ti nib) treats leukemia. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.
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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Sprycel
They need to know if you have any of these conditions:
Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the tablets whole. You can take it with or without food. If it upsets your stomach, take it with food. Your care team may change your dose or tell you stop taking this medication if you get side effects. Do not change your dose or stop taking it unless your care team tells you to.
Take products with aluminum or magnesium in them at a different time of day than this medication. Take antacids 2 hours BEFORE or 2 hours AFTER this medication.
Do not take this medication with grapefruit juice.
Handling this medication may be harmful. Wear gloves while touching the medication. Talk to your care team about how to handle this medication. Special instructions may apply.
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Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 1 year for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, skip it. Take your next dose at the normal time. Do not take extra or 2 doses at the same time to make up for the missed dose.
Do not take this medication with any of the following:
This medication may also interact with the following:
This medication may affect how other medications work, and other medications may affect the way this medication works. Talk with your care team about all of the medications you take. They may suggest changes to your treatment plan to lower the risk of side effects and to make sure your medications work as intended.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your care team for regular checks on your progress. It may be some time before you see the benefit from this medication.
You may need blood work while taking this medication.
This medication may increase your risk to bruise or bleed. Call your care team if you notice any unusual bleeding.
Height and weight growth of a child taking this medicine will be monitored closely.
Talk to your care team if you or your partner wish to become pregnant or think either of you might be pregnant. This medication can cause serious birth defects if taken during pregnancy and for 30 days after stopping therapy. A reliable form of contraception is recommended while taking this medication and for 30 days after stopping therapy. Talk to your care team about effective forms of contraception. Do not breast-feed while taking this medication and for 2 weeks after stopping therapy.
If you are pregnant or may get pregnant, do not handle broken or crushed tablets of this medication. If you are pregnant and come into contact with broken or crushed tablets, contact your care team. Exposure to whole tablets is not expected to cause harm as long as they are not swallowed.
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This medication may cause infertility. Talk to your care team if you are concerned about your fertility.
Side effects that you should report to your care team as soon as possible:
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Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.