What is this medication?
PYRIDOSTIGMINE (peer id oh STIG meen) can help with muscle strength. It is used to treat myasthenia gravis. It is also used to reverse the effects of some muscle relaxers.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Regonol
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
•difficulty passing urine
•irregular, slow heartbeat
•stomach or bowel obstruction or ulcers
•an unusual or allergic reaction to pyridostigmine, benzyl alcohol, bromides, other medicines, foods, dyes, or preservatives
•pregnant or trying to get pregnant
How should I use this medication?
This medicine is for injection into a muscle or a vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
This does not apply.
What may interact with this medication?
Do not take this medicine with any of the following medications:
•other medicines for myasthenia gravis like neostigmine
This medicine may also interact with the following medications:
•medicines that block muscle or nerve pain
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Your condition will be monitored carefully while you are receiving this medicine. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.
What side effects may I notice from receiving this medication?
Side effects that you should report to your doctor or health care professional as soon as possible:
•allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
•changes in vision
•muscle cramps, spasm
•slow or irregular heartbeat
•stomach cramps, pain
•unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
•diarrhea, especially at start of treatment
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medication?
This drug is given in a hospital or clinic and will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy