What is this medication?

STREPTOMYCIN (strep toe MYE sin) is an aminoglycoside antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

•hearing problems

•kidney disease

•an unusual or allergic reaction to streptomycin, other aminoglycosides or medicines, sulfites, foods, dyes or preservatives

•pregnant or trying to get pregnant

•breast-feeding

How should I use this medication?

This medicine is for injection into a muscle. It is usually given by a health care professional in a hospital or clinic setting.

If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

Do not take this medicine with any of the following medications:

•cephaloridine

•cidofovir

•colistin

•cyclosporine

•other aminoglycoside antibiotics

•polymyxin

•viomycin

This medicine may also interact with the following medications:

•anesthesia drugs

•birth control pills

•diuretics

•muscle relaxers

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse. Your condition, including your hearing and lab work, will be monitored while you are taking this medicine.

This medicine may cause a decrease in vitamin B6 and vitamin B12. You should make sure that you get enough vitamin B6 and vitamin B12 while you are taking this medicine. Discuss the foods you eat and the vitamins you take with your health care professional.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

•allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

•breathing problems

•change in amount or color of urine

•change in hearing

•fever

•loss of balance

•pain, tingling, numbness in the hands or feet

•redness, blistering, peeling or loosening of the skin, including inside the mouth

•unusual bleeding or bruising

•unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

•headache

•nausea, vomiting

•pain or swelling at site where injected

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This drug is given in a hospital or clinic and will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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