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Basiliximab injection

Basiliximab stops your body from rejecting a transplanted kidney. A kidney transplant is a procedure where a new donor kidney is placed in your body. This medication is an injection that a healthcare provider will give you in a hospital or clinic setting.

What is this medication?

BASILIXIMAB (ba sil IK si mab) is used to stop your body from attacking or rejecting your transplanted organ (kidney).

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Simulect

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • infection
  • an unusual or allergic reaction to basiliximab, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medication?

This medicine is injected into a vein. It is given by a health care provider in a hospital or clinic setting.

Talk to your health care provider about the use of this medicine in children. While it may be prescribed to children for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply. This medicine is not for regular use.

What may interact with this medication?

Do not take this medicine with any of the following medications:

  • live vaccines

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medicine.

This medicine may increase your risk of getting an infection. Call your health care provider for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.

Women must use a form of birth control while taking this medicine. Women will also need to take it for 4 months after stopping the medicine. There is potential for serious harm to an unborn child. Tell your health care provider right away if you think you might be pregnant. Do not breast-feed an infant while taking this medicine.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions (skin rash, itching or hives; swelling of the face, lips, or tongue)
  • infection (fever, chills, cough, sore throat, pain or trouble passing urine)
  • trouble breathing

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation
  • diarrhea
  • headache
  • nausea, vomiting
  • pain, redness, or irritation at site where injected
  • stomach pain
  • tremors
  • trouble sleeping
  • upset stomach

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medicine is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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