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Lidocaine Patches

What is this medication?

LIDOCAINE (LYE doe kane) treats pain. It works by numbing a specific area of the body, which blocks pain signals going to the brain. It belongs to a group of medications called local anesthetics.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): ALOCANE, Aspercreme with Lidocaine, AsperFlex, Blue-Emu, DermacinRx Lidocan, DermacinRx Lidocan II, DermacinRx Lidocan III, DermacinRx Lidocan IV, DermacinRx Lidocan V, DermacinRx Lidocan VI, DermacinRx Lidocan VII, DermacinRx Lidotral, DermacinRx PHN Pak, DERMALID, GEN7T, LidaFlex, Lido King Maximum Strength, Lidocan, LIDOCANNA, Lidocare, Lidoderm, Lidofore, LidoPure, LidoReal-30, Lidotrode, Lidozo, Salonpas Lidocaine, Tridacaine, Ultra Lido, Xyliderm, ZTlido, Zylotrol

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • G6PD deficiency
  • Heart disease
  • Kidney disease
  • Liver disease
  • Skin conditions or sensitivity
  • An unusual or allergic reaction to lidocaine, parabens, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

How should I use this medication?

This medication is for external use only. Use it as directed on the prescription label. Do not apply to burned or damaged skin. Do not use it more often than directed. Keep using it unless your care team tells you to stop.

Talk to your care team about the use of this medication in children. Special care may be needed.

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Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medication?

This medication may interact with the following:

  • Acetaminophen
  • Certain antibiotics, such as dapsone, nitrofurantoin, aminosalicylic acid, sulfasalazine
  • Certain medications for seizures, such as phenobarbital, phenytoin, valproic acid
  • Chloroquine
  • Cyclophosphamide
  • Dofetilide
  • Flutamide
  • Hydroxyurea
  • Ifosfamide
  • Local anesthetics, such as lidocaine, pramoxine, tetracaine
  • MAOIs, such as Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • Metoclopramide
  • Moricizine
  • Nitroglycerin
  • Primaquine
  • Saquinavir
  • Quinine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.

Be careful to avoid injury while the area is numb, and you are not aware of pain.

If you are going to need surgery, an MRI, CT scan, or other procedure, tell your care team that you are using this medication. You may need to remove the patch before the procedure.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Headache, unusual weakness or fatigue, shortness of breath, nausea, vomiting, rapid heartbeat, blue skin or lips, which may be signs of methemoglobinemia
  • Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Change in skin color
  • Irritation at application site

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

See product for storage information. Each product may have different instructions. Get rid of any unused medication after the expiration date.

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To get rid of medications that are no longer needed or have expired:

  • Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
  • If you cannot return the medication, ask your pharmacist or care team how to get rid of this medication safely.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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