What is this medication?
CLOMIPHENE (KLOE mi feen) treats irregular or absent ovulation in people trying to get pregnant. It works by helping your body produce an egg (ovulation), which increases the chance of pregnancy.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Clomid, Serophene
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
- Adrenal gland disease
- Blood vessel disease or blood clots
- Cyst on the ovary
- Liver disease
- Ovarian cancer
- Pituitary gland disease
- Vaginal bleeding that has not been evaluated
- An unusual or allergic reaction to clomiphene, other medications, foods, dyes, or preservatives
- Pregnant (should not be used if you are already pregnant)
How should I use this medication?
Take this medication by mouth with a glass of water. Follow the directions on the prescription label. Take exactly as directed for the exact number of days prescribed. Take your doses at regular intervals. Most women take this medication for a 5-day period, but the length of treatment may be adjusted. Your care team will give you a start date for this medication and will give you instructions on proper use. Do not take your medication more often than directed.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medication?
- Herbal or dietary supplements, like blue cohosh, black cohosh, chasteberry, or DHEA
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Make sure you understand how and when to use this medication. You need to know when you are ovulating and when to have sexual intercourse. This will increase the chance of a pregnancy.
Visit your care team for regular checks on your progress. You may need tests to check the hormone levels in your blood or you may have to use home-urine tests to check for ovulation. Try to keep any appointments.
Compared to other fertility treatments, this medication does not greatly increase your chances of having multiple babies. An increased chance of having twins may occur in roughly 5 out of every 100 women who take this medication.
Stop taking this medication at once and contact your care team if you think you are pregnant.
This medication is not for long-term use. Most women that benefit from this medication do so within the first three cycles (months). Your care team will monitor your condition. This medication is usually used for a total of 6 cycles of treatment.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Do not stand or sit up quickly. This reduces the risk of dizzy or fainting spells.
Drinking alcoholic beverages or smoking tobacco may decrease your chance of becoming pregnant. Limit or stop alcohol and tobacco use during your fertility treatments.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Change in vision
- Ovarian hyperstimulation syndrome—stomach or pelvic pain, bloating, nausea, vomiting, diarrhea, weight gain
- Pancreatitis—severe stomach pain that spreads to your back or gets worse after eating or when touched, fever, nausea, vomiting
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
- Breast pain or tenderness
- Hot flashes
- Irregular menstrual cycles or spotting
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medication?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from heat, light, and moisture. Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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