Ergotamine; Caffeine Oral Tablets
What is this medication?
ERGOTAMINE; CAFFEINE (er GOT a meen; KAF een;) is part of a group of medicines called ergot alkaloids. It is used to treat or prevent migraine and cluster headaches.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Cafergot
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
- heart or blood vessel disease
- high blood pressure
- kidney disease
- liver disease
- poor circulation
- an unusual or allergic reaction to ergotamine, caffeine, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
How should I use this medication?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not stop taking except on the advice of your doctor or health care professional.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
This does not apply. You should only take this medicine at the first sign of an attack. Do not take double or extra doses.
What may interact with this medication?
Do not take this medicine with any of the following medications:
- antifungal drugs like fluconazole, itraconazole, ketoconazole or voriconazole
- certain antibiotics like erythromycin, clarithromycin, and troleandomycin
- grapefruit juice
- medicines called nitrates like isosorbide and nitroglycerin
- medicines for colds, flu, or breathing difficulties like phenylephrine and pseudoephedrine
- medicines for HIV or AIDS called protease inhibitors, delavirdine, efavirenz, nelfinavir
- medicines for migraine headache like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, and zolmitriptan
- other ergot alkaloids like bromocriptine, cabergoline, dihydroergotamine, ergoloid mesylates, ergonovine, methylergonovine, and methysergide
This medicine may also interact with the following medications:
- medicines for high blood pressure, especially beta-blockers
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Check with your doctor or health care professional if you do not get relief from your headaches after using this medicine. You may need to be changed to a different kind of medicine to treat your migraines.
This medicine decreases the circulation of blood to your skin, fingers, and toes. You may get more sensitive to the cold. Elderly patients are more likely to feel this effect. Dress warmly and avoid long exposure to the cold.
This medicine contains caffeine. Limit your intake of caffeinated beverages on the days that you use this medicine.
If you take migraine medicines for 10 or more days a month, your migraines may get worse. Keep a diary of headache days and medicine use. Contact your healthcare professional if your migraine attacks occur more frequently.
What side effects may I notice from receiving this medication?
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- breathing problems
- chest pain or tightness
- cold hands or feet
- fast, slow, or pounding heartbeat
- leg or arm pain or cramps
- rectal discomfort or sores
- stomach pain
- swelling of hands, ankles, or feet
- tingling, pain, or numbness in the face, hands, or feet
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
- increased urination
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medication?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Keep container tightly closed. Throw away any unused medicine after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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