What is this medication?

OMEPRAZOLE (oh ME pray zol) is used to treat heartburn, stomach ulcers, reflux disease, or other conditions that cause too much stomach acid. It works by reducing the amount of acid in the stomach. It belongs to a group of medications called PPIs.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Prilosec

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

How should I use this medication?

Take this medication by mouth with a glass of water. Follow the directions on the label. Do not cut, crush or chew this medication. Swallow the capsules whole. You may open the capsule and put the contents in 1 tablespoon of applesauce. Swallow the medication and applesauce right away. Do not chew the medication or applesauce. Take this medication before a meal. Take your medication at regular intervals. Do not take your medication more often than directed. Do not stop taking except on your care team's advice.

Talk to your care team about the use of this medication in children. While this medication may be prescribed for children as young as 2 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

Do not take this medication with any of the following:

This medication may also interact with the following:

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

It can take several days before your stomach pain gets better. Check with your care team if your condition does not start to get better, or if it gets worse.

Do not treat diarrhea with over the counter products. Contact your care team if you have diarrhea that lasts more than 2 days or if it is severe and watery.

You may need blood work done while you are taking this medication.

Using this medication for a long time may weaken your bones. The risk of bone fractures may be increased. Talk to your care team about your bone health.

Using this medication for a long time may cause growths (polyps) in the stomach. They usually don't cause any symptoms. They are usually not cancerous. Contact your care team if you notice pain or tenderness when you press your stomach, have nausea, or see bloody or black, tar-like stools.

This medication may cause a decrease in vitamin B12. You should make sure that you get enough vitamin B12 while you are taking this medication. Discuss the foods you eat and the vitamins you take with your care team.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or expired:

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Copyright ©2022 Elsevier Inc. All Rights Reserved. Terms of Use.

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy