Azelastine; Fluticasone nasal spray

Azelastine nasal spray is a histamine blocker that combines with fluticasone, a corticosteroid. This nasal spray treats the symptoms of allergies like sneezing and a runny or stuffy nose. The brand name of this medication is Dymista®. Follow the instructions on the label to spray this medication into your nose as directed.

What is this medication?

AZELASTINE; FLUTICASONE (a ZEL as teen; floo TIK a sone) is a combination of a histamine blocker and a corticosteroid. This medicine is used to treat the symptoms of allergies like sneezing, itching, and runny or stuffy nose.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Dymista

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What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • cataracts
  • glaucoma
  • infection, like tuberculosis, herpes, or fungal infection
  • recent surgery or injury of the nose or sinuses
  • taking a corticosteroid by mouth
  • an unusual or allergic reaction to azelastine, fluticasone, steroids, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medication?

This medicine is for use in the nose. Follow the directions on the prescription label. Shake well before using. Do not use more often than directed. Make sure that you are using your nasal spray correctly. Ask you doctor or health care provider if you have any questions.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

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What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medication?

  • alcohol
  • certain medicines for anxiety or sleep
  • cimetidine
  • ketoconazole
  • metyrapone
  • other antihistamines
  • some medicines for HIV
  • vaccines

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

You may get drowsy or dizzy. Drinking alcohol or taking medicine that causes drowsiness can make this worse. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you.

This medicine may increase your risk of getting an infection. Tell your doctor or health care professional if you are around anyone with measles or chickenpox, or if you develop sores or blisters that do not heal properly.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • changes in vision
  • fast heartbeat
  • flu-like symptoms
  • high blood pressure
  • infection
  • nose bleeding, sores
  • white patches or sores in the mouth or nose

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • changes in smell or taste
  • cough
  • feeling tired
  • headache
  • larger appetite or weight gain
  • nose or throat irritation
  • sneezing

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children.

Store upright and tightly closed at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Do not freeze. Throw away any unused medicine after the expiration date or after 120 sprays, whichever comes first.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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