Tobramycin solution for inhalation

What is this medication?

TOBRAMYCIN (toe bra MYE sin) is an aminoglycoside antibiotic. It is used to treat or prevent certain kinds of bacterial infections in the lungs. It will not work for colds, flu, or other viral infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): BETHKIS, Kitabis Pak, Tobi

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

•balance problems

•hearing problems

•kidney disease

•myasthenia gravis

•Parkinson's disease

•an unusual or allergic reaction to tobramycin, other aminoglycosides or medicines, sulfites, foods, dyes or preservatives

•pregnant or trying to get pregnant

•breast-feeding

How should I use this medication?

This medicine is for inhalation using a nebulizer. Nebulizers make a liquid into an aerosol that you breathe in through your mouth or your mouth and nose and into your lungs. You will be taught how to use your nebulizer. Follow the directions on your prescription label. Do not use more often than directed.

You will get an information sheet with each prescription and refill. Read this sheet carefully each time. This sheet may change.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years old for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as possible anytime up to 6 hours before the next dose. If it is less than 6 hours before the next dose, skip the missed dose and take your next dose as its regularly scheduled time. Do not take double or extra doses.

What may interact with this medication?

Do not take this medicine with any of the following medications:

•cidofovir

•cisplatin

•colistin

•ethacrynic acid

•furosemide

•mannitol

•other aminoglycoside antibiotics

•polymyxin

•urea

•vancomycin

•viomycin

This medicine may also interact with the following medications:

•birth control pills

•diuretics

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your doctor or health care professional as directed. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

This medicine may cause a decrease in vitamin B6 and vitamin B12. You should make sure that you get enough vitamin B6 and vitamin B12 while you are taking this medicine. Discuss the foods you eat and the vitamins you take with your health care professional.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

•allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

•breathing problems

•change in amount or color of urine

•change in hearing

•dizziness

•fever or infection

•loss of balance

•redness, blistering, peeling or loosening of the skin, including inside the mouth

•unusual bleeding or bruising

•unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

•diarrhea

•changes in voice

•cough

•headache

•nausea, vomiting

•runny nose

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children.

Store in the refrigerator between 2 and 8 degrees C (36 and 46 degrees F). You can also store this medicine at room temperature, up to 25 degrees C (77 degrees F) and throw away any unused medicine after 28 days. Protect from light. Do not use if the medicine is cloudy. Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.