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Japanese Encephalitis Vaccine Injection

The Japanese encephalitis vaccine prevents Japanese encephalitis infections. This infection causes fever, headaches and neck pain. It can also affect cognitive functioning, leading to confusion and behavior changes. A healthcare provider will give you two doses of this vaccine, the second dose occurs 28 days after the first dose.

What is this medication?

JAPANESE ENCEPHALITIS VACCINE (jap uh NEEZ en sef uh LAHY tis vak SEEN) reduces the risk of Japanese encephalitis (JE). It does not treat Japanese encephalitis. It is still possible to get Japanese encephalitis after receiving this vaccine, but the symptoms may be less severe or not last as long. It works by helping your immune system learn how to fight off a future infection.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Ixiaro

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Hemophilia
  • Immune system problems
  • Low blood counts, such as low white cells, platelets, or red cell counts
  • Take medications that treat or prevent blood clots
  • An unusual or allergic reaction to Japanese encephalitis virus vaccine, other vaccines, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breastfeeding

How should I use this medication?

This vaccine is injected into a muscle. It is given by your care team. Two doses are given. The second dose is given 28 days after the first dose.

A copy of Vaccine Information Statements will be given before each vaccination. Be sure to read this information carefully each time. This sheet may change often.

Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 2 months for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

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What if I miss a dose?

Keep appointments for follow-up doses as directed. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.

What may interact with this medication?

  • Medications that suppress your immune system, such as medications for cancer
  • Steroid medications, such as prednisone or cortisone
  • Vaccines

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Report any side effects to your care team right away.

This vaccine may not fully protect everyone. This vaccine does not prevent all types of encephalitis.

Protect yourself from mosquito bites.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Diarrhea
  • Fatigue
  • Fever
  • Headache
  • Irritability
  • Muscle pain
  • Pain, redness, or irritation at injection site

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This vaccine is only given by your care team. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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