Lomitapide lowers your blood cholesterol level caused by certain genetic conditions. Cholesterol is a waxy substance that your body needs to function. This medication comes in a capsule form that you can take with water as directed. Take it on an empty stomach and don’t take it with grapefruit juice.
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LOMITAPIDE (loe MI ta pide) treats high cholesterol. It works by reducing the amount of cholesterol made by your body. Changes to diet and exercise are often combined with this medication.
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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Juxtapid
They need to know if you have any of these conditions:
Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the capsules whole. Take it on an empty stomach, at least 2 hours after food. Keep taking it unless your care team tells you to stop.
Take this medication at least 4 hours before or at least 4 hours after administration of a bile acid sequestrant.
Do not take this medication with grapefruit juice.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
It is important not to miss any doses. Talk to your care team about what to do if you miss a dose.
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Do not take this medication with any of the following:
This medication may also interact with the following:
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
Drinking alcohol with this medication can increase the risk of side effects.
Talk to your care team if you wish to become pregnant or think you might be pregnant. This medication can cause serious birth defects if taken during pregnancy. Estrogen and/or progestin hormones may not work as well while you are taking this medication. A barrier contraceptive, such as a condom or diaphragm, is recommended. Talk to your care team about other forms of contraception.
Talk to your care team before breastfeeding. Changes to your treatment plan may be needed.
Taking this medication is only part of a total heart healthy program. Ask your care team if there are other changes you can make to improve your overall health.
Side effects that you should report to your care team as soon as possible:
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Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children and pets.
Store between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Keep the container tightly closed. Get rid of any unused medication after the expiration date.
To get rid of medication that is no longer needed or has expired:
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NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.