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Aluminum Chloride Topical Solution

What is this medication?

ALUMINUM CHLORIDE (a LOO mi num klor ide) treats excessive sweating. It works by blocking your sweat pores, which prevents sweat from reaching the surface. It belongs to a group of medications called antiperspirants.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Drysol, Hypercare, Xerac AC

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • An unusual or allergic reaction to aluminum chloride, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breastfeeding

How should I use this medication?

This medication is for external use only. Follow the directions on the prescription label. Make sure the skin is dry before use. Apply to the affected area as directed by your care team, usually at bedtime. Avoid contact with broken, irritated or recently shaved skin. Do not use your medication more often than directed.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medication?

Interactions are not expected. Do not use any other skin products on the affected area without asking your care team.

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This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

You may notice a decrease in sweating after 2 treatments. Call your care team if your condition does not start to get better or if it gets worse.

To help increase the effect of this medication, your care team may tell you to cover the treated area with plastic wrap held in place by a snug-fitting t-shirt, mitten, or sock. Do not use tape to hold the plastic wrap in place.

This medication may discolor fabrics and may be harmful to certain metals. Avoid contact with clothing and jewelry.

Do not use this medication near open flame.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Mild skin irritation, redness, or dryness

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

  • Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
  • If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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