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GOSERELIN (GOE se rel in) treats prostate cancer and breast cancer. It works by decreasing levels of the hormones testosterone and estrogen in the body. This prevents prostate and breast cancer cells from spreading or growing. It may also be used to treat endometriosis. This is a condition where the tissue that lines the uterus grows outside the uterus. It works by decreasing the amount of estrogen your body makes, which reduces heavy bleeding and pain. It can also be used to help thin the lining of the uterus before a surgery used to prevent or reduce heavy periods.
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Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Zoladex, Zoladex 3-Month
They need to know if you have any of these conditions:
This medication is injected under the skin. It is given by your care team in a hospital or clinic setting.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.
Do not take this medication with any of the following:
This medication may also interact with the following:
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Your symptoms may appear to get worse during the first weeks of this therapy. Tell your care team if your symptoms do not start to get better or if they get worse after this time.
Using this medication for a long time may weaken your bones. If you smoke or frequently drink alcohol you may increase your risk of bone loss. A family history of osteoporosis, chronic use of medications for seizures (convulsions), or corticosteroids can also increase your risk of bone loss. The risk of bone fractures may be increased. Talk to your care team about your bone health.
This medication may increase blood sugar. The risk may be higher in patients who already have diabetes. Ask your care team what you can do to lower your risk of diabetes while taking this medication.
This medication should stop regular monthly menstruation in women. Tell your care team if you continue to menstruate.
Talk to your care team if you wish to become pregnant or think you might be pregnant. This medication can cause serious birth defects if taken during pregnancy or for 12 weeks after stopping treatment. Talk to your care team about reliable forms of contraception.
Do not breastfeed while taking this medication.
This medication may cause infertility. Talk to your care team if you are concerned about your fertility.
Side effects that you should report to your care team as soon as possible:
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Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
This medication is given in a hospital or clinic. It will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.