ISOSORBIDE DINITRATE (eye soe SOR bide dye NYE trate) prevents chest pain (angina). It works by relaxing blood vessels, which decreases the amount of work the heart has to do. It belongs to a group of medications called nitrates. Do not use it to treat sudden chest pain.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Isordil Titradose, Sorbitrate, Wesorbide
They need to know if you have any of these conditions:
Take this medication by mouth with a glass of water. Follow the directions on the prescription label. Take this medication on an empty stomach, at least 30 minutes before or 2 hours after food. Do not take with food. Take your medication at regular intervals. Do not take your medication more often than directed. Do not stop taking this medication suddenly or your symptoms may get worse. Ask your care team how to gradually reduce the dose.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Do not take this medication with any of the following:
This medication may also interact with the following:
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Check your heart rate and blood pressure regularly while you are taking this medication. Ask your care team what your heart rate and blood pressure should be and when you should contact him or her. Tell your care team if you feel your medication is no longer working.
You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can make you more dizzy, and increase flushing and rapid heartbeats. Avoid alcoholic drinks.
Do not treat yourself for coughs, colds, or pain while you are taking this medication without asking your care team for advice. Some ingredients may increase your blood pressure.
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children.
Store at room temperature, approximately 25 degrees C (77 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.