IRB Study Number 22-958
Status Recruiting
Locations Cleveland Clinic Main Campus, Cleveland Clinic Weston Hospital
Institute Digestive Disease & Surgery Institute
Description
This study is for adults with inflammatory bowel disease (IBD) — Crohn’s disease, ulcerative colitis, or IBD-unclassified — who are having intestinal surgery for IBD at Cleveland Clinic or another participating center.
The goal is to build a long-term surgical cohort to understand how IBD surgery and medical treatment affect recovery, complications, and disease control over time.
If you join, you will:
Have your usual IBD surgery and usual medical care (the study does not change your treatment),
Allow the team to collect information from your medical record about your IBD, medications, and surgeries,
Be asked to complete questionnaires about your health and quality of life at set times after surgery, and
Be asked to provide blood, stool, and leftover tissue samples around the time of surgery and about 3 months later, when possible.
There are no extra operations done just for the study. Extra blood/stool samples and questionnaires are collected around routine care visits.
Inclusion Criteria
Age 18 years or older
Diagnosis of Crohn’s disease, ulcerative colitis, or IBD-unclassified (IBD-U)
Being treated at or referred to a participating site for intestinal surgery for IBD
Able to be enrolled before surgery or within 48 hours after surgery
Exclusion Criteria
Unable to provide informed consent
Unable to provide an email address
Seen only for a one-time consultation or second opinion and not having IBD surgery at the participating center
Students or employees who are directly supervised by one of the investigators
Having other abdominal or pelvic surgery without IBD intestinal surgery
e.g., adhesiolysis, incisional hernia repair, cholecystectomy, appendectomy, transplant, urologic, or gynecologic surgery only
Surgery done for presumed IBD but pathology later shows no IBD (for example lymphoma, infection such as TB, or another condition)
Surgery for isolated perianal Crohn’s disease only
