Details

IRB Study Number 22-971

Status Recruiting

Institute Respiratory Institute

Description

Description

The objective of this study is to prospectively characterize individuals with a confirmed PI*MZ genotype and obtain biospecimens to assess their inflammatory profile.

Inclusion Criteria

Inclusion Criteria

The inclusion criteria for the Aim 1 cohorts are: a confirmed PI*MZ genotype, FEV1% predicted ≥35%, and a ≥10 pack-year smoking history.

Exclusion Criteria

Exclusion Criteria

Exclusion criteria are inability to consent, history of interstitial lung disease (self-reported, documented or radiographic), self-reported smoking in the last 6 months.