IRB Study Number 5024
Status Recruiting
Locations Beachwood Family Health and Surgery Center, Moll Cancer Center at Fairview Hospital - DO NOT USE, Hillcrest Hospital, Independence Family Health Center, Cleveland Clinic Main Campus, Cancer Center, Mansfield, North Coast Cancer (Sandusky), South Pointe Hospital, Strongsville Family Health and Surgery Center, Wooster Family Health Center
Institute Taussig Cancer Institute
Description
none
Inclusion Criteria
Normal volunteers and patients with hematologic disorders (adults and children) evaluated and/or treated at the Cleveland Clinic Foundation will be the source of blood, surgical specimen and bone marrow.The normal volunteers will be recruited through an advertisement flyer to be posted in appropriated boards throughout the institution or inter-institutional publications such as Innerpulse (see Appendix A). Patients include individuals with bone marrow failure syndromes, like aplastic anemia, paroxysmal nocturnal hemoglobinuria, myelodysplasia, Fanconi's anemia, and single lineage cytopenias.Patients with malignant disease include those with acute and chronic forms of leukemia including myeloproliferative disorders like mast cell diseases, multiple myeloma, myelofibrosis. Patients with constitutional anemias include patients with thalassemia, sickle cell disease, and all forms of lymphoma. Patients with immune-mediated processes include those with thrombocytopenic thrombotic purpura and idiopathic thrombocytopenic purpura.
Exclusion Criteria
none
