IRB Study Number 19-1437
Status Recruiting
Location Cleveland Clinic Main Campus
Institute Taussig Cancer Institute
Description
The MPN-RC Research Tissue Bank plans to collect and store tissue specimens from patients with MPN including (polycythemia vera [PV], primary myelofibrosis [PMF], and essential thrombocythemia [ET]). These tissue samples will be used to conduct laboratory investigations within the laboratory-based scientific projects of the MPN-RC to help define mechanisms involved in the pathophysiology, progression and effects of treatment of myelofibrosis.
Inclusion Criteria
Newly diagnosed patients diagnosed with Philadelphia chromosome negative myeloproliferative neoplasms (MPN) polycythemia vera (PV), prefibrotic myelofibrosis (Pre-PMF), overt primary myelofibrosis (PMF), essential thrombocythemia (ET), and myeloproliferative neoplasm blast phase (MPN-blast phase) as well as patients previously treated for an MPN.
Signed informed consent is required from each patient at the time of enrollment.
Exclusion Criteria
Patients currently participating in experimental treatment arms of MPN-RC protocols, or other experimental treatment protocols.
