Brimonidine Gel

What is this medication?

BRIMONIDINE (bri MOE ni deen) treats rosacea. It works by narrowing the blood vessels under the skin. This reduces flushing and skin color changes.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Mirvaso

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What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Buerger's disease
  • Depression
  • Heart disease
  • Irritated skin or open sores
  • Raynaud's phenomenon
  • Scleroderma
  • Sjogren's syndrome
  • An unusual or allergic reaction to brimonidine, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

How should I use this medication?

This medication is for external use only. Use your medication at regular intervals. Do not use it more often than directed. Do not stop using except on the advice of your care team.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

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What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medication?

  • Alcohol
  • Certain medications for blood pressure, heart disease, irregular heartbeat
  • MAOIs, such as Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • Medications that cause drowsiness or tiredness

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

Do not get this medication in your eyes. If you do, rinse out with plenty of cool tap water.

If anyone, especially a child, accidentally swallows this medication, they may have serious side effects and need to be treated in a hospital. Get medical help right away if anyone swallows this medication and has lack of energy, trouble breathing or stops breathing, a slow heartbeat, confusion, sweating, restlessness, muscle spasms, or twitching.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
  • Slow heartbeat—dizziness, feeling faint or lightheaded, confusion, trouble breathing, unusual weakness or fatigue

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Acne
  • Facial flushing, redness
  • Mild skin irritation, redness, or dryness
  • Pale skin, loss of color around application site

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Copyright ©2024 Elsevier Inc. All Rights Reserved.

Terms of use.

Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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