Cromolyn Solution

Cromolyn is a medication that manages symptoms of mastocytosis. This condition causes your body to produce too many mast cells. Mast cells are immune cells that build up under your skin and/or in your bones, intestines and other organs.

What is this medication?

CROMOLYN (KROE moe lin) helps manage the symptoms of mastocytosis, a condition that causes the body to produce too many mast cells. It works by reducing the release of substances in your body that cause symptoms such as diarrhea, stomach pain, nausea, vomiting, flushing, itching, and headache. It belongs to a group of medications called mast cell stabilizers.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Gastrocrom

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What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Kidney disease
  • Liver disease
  • An unusual or allergic reaction to cromolyn, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

How should I use this medication?

Take this medication by mouth. Follow the directions on the prescription label. Take one-half hour before meals and at bedtime. Open the foil pouch and take out the ampule(s) you need for your dose. Open the ampule by twisting off the tab. Squeeze the medication into a glass of water. Do not mix with other drinks or food. Stir well. Drink all of the mixture. Take your medication at regular intervals. Do not take it more often than directed.

Talk to your care team about the use of this medication in children. While this medication may be prescribed for children as young as 2 years old for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

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What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

Interactions are not expected.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Your care team may adjust your dose for best results. Talk to your care team before you change your dose or stop taking this medication.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Diarrhea
  • Headache
  • Irritability
  • Muscle pain
  • Nausea
  • Stomach pain

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Keep in the foil pouch until ready to use. Do not use if medication is cloudy, has solid pieces, or is discolored. Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Copyright ©2024 Elsevier Inc. All Rights Reserved.

Terms of use.

Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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