Topiramate is a medication that treats epilepsy by preventing and managing seizures. This medication can also prevent migraine headaches. Topiramate works by calming overactive nerves in your body. Brand names for this medication are Topamax® and Topiragen®.
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TOPIRAMATE (toe PYRE a mate) prevents and controls seizures in people with epilepsy. It may also be used to prevent migraine headaches. It works by calming overactive nerves in your body.
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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Topamax, Topiragen
They need to know if you have any of these conditions:
Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. Do not cut, crush or chew this medicine. Swallow the tablets whole. You can take it with or without food. If it upsets your stomach, take it with food. Keep taking it unless your care team tells you to stop.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 2 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
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NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, take it as soon as you can unless it is within 6 hours of the next dose. If it is within 6 hours of the next dose, skip the missed dose. Take the next dose at the normal time. Do not take double or extra doses.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
Do not suddenly stop taking this medication. You may develop a severe reaction. Your care team will tell you how much medication to take. If your care team wants you to stop the medication, the dose may be slowly lowered over time to avoid any side effects.
Wear a medical ID bracelet or chain. Carry a card that describes your condition. List the medications and doses you take on the card.
This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.
This medication may cause serious skin reactions. They can happen weeks to months after starting the medication. Contact your care team right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. You may also notice a red rash with swelling of the face, lips, or lymph nodes in your neck or under your arms.
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This medication may cause thoughts of suicide or depression. This includes sudden changes in mood, behaviors, or thoughts. These changes can happen at any time but are more common in the beginning of treatment or after a change in dose. Call your care team right away if you experience these thoughts or worsening depression.
This medication may slow your child's growth if it is taken for a long time at high doses. Your child's care team will monitor your child's growth.
Using this medication for a long time may weaken your bones. The risk of bone fractures may be increased. Talk to your care team about your bone health.
Discuss this medication with your care team if you may be pregnant. Serious birth defects can occur if you take this medication during pregnancy. There are benefits and risks to taking medications during pregnancy. Your care team can help you find the option that works for you. Contraception is recommended while taking this medication. Estrogen and progestin hormones may not work as well while you are taking this medication. Your care team can help you find the option that works for you.
Talk to your care team before breastfeeding. Changes to your treatment plan may be needed.
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Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Keep the container tightly closed. Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.