Rabeprazole Capsules

What is this medication?

RABEPRAZOLE (ra BE pray zole) treats heartburn, stomach ulcers, reflux disease, or other conditions caused by too much stomach acid. It works by reducing the amount of acid in the stomach. It belongs to a group of medications called PPIs.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Aciphex Sprinkle

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What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Liver disease
  • Low levels of calcium, magnesium, or potassium in the blood
  • Lupus
  • An unusual or allergic reaction to rabeprazole, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

How should I use this medication?

Take this medication by mouth. Follow the directions on the prescription label. Do not swallow whole, crush, or chew the granules. To take this medication, you can sprinkle the granules on a small amount of soft food like apple sauce, fruit or vegetable based baby food, or yogurt. You can also sprinkle them on a small amount of infant formula, apple juice, or a pediatric electrolyte solution. The food or liquid must be at or below room temperature. Swallow the entire dose. Take your dose within 15 minutes of mixing it with food or liquid. Do not save it for later. Take your dose 30 minutes before a meal. Take your medication at regular intervals. Do not take your medication more often than directed.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your care team about the use of this medication in children. While this medication may be prescribed for children as young as 1 year for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

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What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

Do not take this medication with any of the following:

  • Atazanavir
  • Nelfinavir

This medication may also interact with the following:

  • Aminophylline or theophylline
  • Amoxicillin
  • Ampicillin
  • Clarithromycin
  • Cyclosporine
  • Diazepam
  • Digoxin
  • Diuretics
  • Iron salts
  • Itraconazole, ketoconazole, voriconazole, or other prescription medications for fungus or yeast infections
  • Methotrexate
  • Phenytoin
  • Warfarin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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What should I watch for while using this medication?

It can take several days before your stomach pain gets better. Check with your care team if your condition does not start to get better, or if it gets worse.

Do not treat diarrhea with over the counter products. Contact your care team if you have diarrhea that lasts more than 2 days or if it is severe and watery.

You may need blood work done while you are taking this medication.

Using this medication for a long time may weaken your bones. The risk of bone fractures may be increased. Talk to your care team about your bone health.

Using this medication for a long time may cause growths (polyps) in the stomach. They usually don't cause any symptoms. They are usually not cancerous. Contact your care team if you notice pain or tenderness when you press your stomach, have nausea, or see bloody or black, tar-like stools.

This medication may cause a decrease in vitamin B12. You should make sure that you get enough vitamin B12 while you are taking this medication. Discuss the foods you eat and the vitamins you take with your care team.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
  • Low magnesium level—muscle pain or cramps, unusual weakness or fatigue, fast or irregular heartbeat, tremors
  • Low vitamin B12 level—pain, tingling, or numbness in the hands or feet, muscle weakness, dizziness, confusion, difficulty concentrating
  • Rash on the cheeks or ams that gets worse in the sun
  • Redness, blistering, peeling, or loosening of the skin, including inside the mouth
  • Severe diarrhea, fever

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Constipation
  • Diarrhea
  • Dry mouth
  • Headache
  • Nausea

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Copyright ©2024 Elsevier Inc. All Rights Reserved.

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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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