Methenamine; Sodium Biphosphate; Phenyl Salicylate; Methylene Blue; Hyoscyamine Capsules or Tablets

What is this medication?

METHENAMINE; SODIUM BIPHOSPHATE; PHENYL SALICYLATE; METHYLENE BLUE; HYOSCYAMINE (meth EN a meen; SOW dee um bi FOS fate; fen il suh LIS uh leyt; METH uh leen bloo; hye oh SYE a meen) relieves symptoms caused by irritation of the urinary tract, such as pain, burning, and passing frequent small amounts of urine. It works by relaxing the muscles of the bladder, which decreases spasms. It is not an antibiotic. It will not treat a urinary tract infection (UTI).

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Azuphen MB, Darcalma, Hyolev MB, MD 20, MSP Blu, Phosenamine, Phosphasal, UR N-C, Uramit, Urelle, Uretron DS, Uribel, Urimar-T, Urimax, Urin DS, UriSym, Uro Blue, Uro-L, Uro-MP, Ustell, UTA, UTICAP, Utira, Utira-C, Utrona, Utrona-C, VILAMIT MB

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Bladder or prostate problems or trouble passing urine
• Glaucoma
• Heart disease
• Myasthenia gravis
• Stomach problems
• An unusual or allergic reaction to hyoscyamine; methenamine; methylene blue; phenyl salicylate; sodium biphosphate, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

How should I use this medication?

Take this medication by mouth with a glass of water. Follow the directions on the prescription label. Take your medication at regular intervals. Do not take it more often than directed. Do not stop taking except on your care team's advice.

Talk to your care team about the use of this medication in children. While this medication may be prescribed for children as young as 7 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

• Antacids
• Atropine
• Antihistamines
• Certain antibiotics, such as sulfacetamide or sulfamethoxazole
• Certain medications for bladder problems, such as oxybutynin or tolterodine
• Certain medications for blood pressure, such as hydrochlorothiazide
• Certain medications for stomach problems, such as dicyclomine or hyoscyamine
• Certain medications for travel sickness, such as scopolamine
• Certain medications for Parkinson disease, such as benztropine or trihexyphenidyl
• Ipratropium
• Ketoconazole
• MAOIs, such as Carbex, Eldepryl, Marplan, Nardil, and Parnate
• Opioids

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Tell your care team if your symptoms do not start to get better or if they get worse.

This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your care team if the problem does not go away or is severe.

You will need to be on a special diet while taking this medication. Ask your care team how many glasses of water or other fluids to drink each day. Also, ask which foods to include and which to avoid to help keep your urine acidic. Your urine must be acidic for this medication to work.

This medication may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye care team if the problem does not go away or is severe.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Blurry vision
• Change in the amount of urine
• Fast or irregular heartbeat
• Trouble passing urine

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

• Blue or blue-green urine or stools
• Dizziness
• Drowsiness
• Dry mouth
• Flushing
• Nausea
• Vomiting

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.