IRB Study Number 22-1414
Status Recruiting
Location Cleveland Clinic Main Campus
Institute Heart and Vascular Institute
Description
The purpose of this study is to characterize the safety, tolerability, efficacy, PK, and PD of MYK-224 in participants with oHCM. Study details include the following:
Study Duration: Approximately 18 to 53 weeks
Study Intervention Duration: Approximately 12 to 45 weeks
Study Visit Frequency: Bi-weekly clinic visits with phone visits on alternate weeks
Inclusion Criteria
18-70 years of age
BMI of 18-37
Diagnosis of obstructive hypertrophic cardiomyopathy
Exclusion Criteria
Active infection
History of cardiac arrest
Women who are pregnant or breastfeeding
