Cleveland Clinic Innovations
Healthcare Innovation and Commercialization, From Discovery to Real-World Impact
Today’s medical innovations are shaping the future of healthcare. Cleveland Clinic Innovations accelerates that progress, transforming ideas from the brightest minds in medicine into patient-centered solutions.
As the commercialization engine of one of the world’s leading research hospitals, we connect discoveries that address healthcare’s greatest unmet needs to business opportunities that can bring them to market. Our team licenses medical technologies, launches healthcare startups and builds strategic collaborations with industry partners, with the goal of bringing therapies and products to patients that improve outcomes, reduce costs and expand access to care.
For industry partners, we’re the gateway into Cleveland Clinic’s integrated healthcare ecosystem. Innovators who share our goals can scale and validate emerging technologies alongside renowned Cleveland Clinic clinicians and researchers.
Partner With Cleveland Clinic Innovations
Our portfolio spans medical devices, therapeutics, diagnostics, digital health and AI-driven healthcare solutions, developed within Cleveland Clinic and grounded in clinical validation.
Driving Impact Across Healthcare Innovation
Together, we are reimagining the health journey by developing and commercializing technologies that streamline hospital operations, reduce costs and connect patients to specific therapies.
A snapshot of our impact in 2025
207
Invention Disclosures
58
License Agreements
207
New Inventors
37
Current Portfolio Companies
What Makes Cleveland Clinic Innovations Different From Traditional Tech Transfer?
Powered by Cleveland Clinic’s global innovation ecosystem:
Cleveland Clinic’s globally recognized ecosystem of research, discovery and unmatched clinical talent fuels our work to solve healthcare’s greatest challenges. Partners who share our vision can leverage the strengths of our vast research network and work alongside clinicians who care for diverse populations and take on some of the most complex cases. In collaboration, we can pressure test new platforms, validate clinical data and derisk products and therapies before they reach the market.
Innovation driven by caregivers:
Cleveland Clinic’s 80,000+ caregivers are problem-solvers by nature, and innovation has always been central to our culture. Across specialties and global patient populations, they identify unmet needs and imagine better ways to solve them. We connect their promising ideas to the resources needed to bring them to market and, by extension, to patients worldwide. And, through co-development partnerships, our caregivers build healthcare solutions side-by-side with industry partners.
Our team’s integrated approach to bringing healthcare innovation to market:
Within Innovations, our experts oversee each stage of the healthcare innovation and technology commercialization process. We match our expertise in intellectual property management, technology development, licensing and startup incubation to our partners' unique needs and offer individualized commercialization pathways to bring innovations to patients at scale.
Cleveland Clinic Innovations 2025 Year in Review: Built on Legacy, Wired for the Future
In 2025, we reimagined what it means to partner with Cleveland Clinic Innovations and expanded the ways we bring healthcare innovations to patients at scale. In doing so, we saw 58 new license agreements and 207 new invention disclosures. We announced a strategic collaboration with Khosla Ventures, one of Silicon Valley’s leading investors in healthcare commercialization and technology – an example of how we’re strategically connecting outside innovation to our world-class ecosystem of research, discovery and clinical talent.
Connect With Us
We are more than a tech transfer office. We are a medical innovations powerhouse. Cleveland Clinic Innovations is changing healthcare for patients around the world. Contact us to partner or learn more about what we do and why we do it.
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