Testing Before Oral Immunotherapy at Cleveland Clinic Children’s
Peanut allergies are one of the most common food allergies in kids. We used to think peanut allergies were lifelong but have learned that roughly 1 in 5 kids eventually outgrow them. For those who don’t, we may recommend OIT. It can help them, and you, worry less about accidental exposure.
It’s important to remember that oral immunotherapy isn’t a cure for food allergies. But it can make it possible for your child to tolerate accidental exposure without a reaction. Not all kids respond to this therapy, so we’ll carefully test your child before we recommend OIT.
If your child has unmanaged asthma or eosinophilic esophagitis (EoE), oral immunotherapy is probably not an option for them. You must also be willing and able to give your child epinephrine injections at home.
Meet Our Oral Immunotherapy Pediatric Team
When your child comes to Cleveland Clinic Children’s for oral immunotherapy, they’ll work with a team of compassionate, experienced providers, including:
- Pediatric allergists (immunologists)
- Pediatric dietitians
- Pediatric behavioral health specialists
- Pediatric nurse practitioners
- Pediatric physician assistants
This team will work with your child and you to develop a personalized treatment plan based on your child’s allergic reactions and overall health. We want you both to feel comfortable with the plan.
0 Providers Who Treat Food Allergies With Oral Immunotherapy
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Our healthcare providers see patients at convenient locations throughout Northeast Ohio and Florida.
Treating Food Allergies With Oral Immunotherapy at Cleveland Clinic Children’s
At Cleveland Clinic Children’s, we only recommend oral immunotherapy if we’re confident your child will benefit from it. OIT can be used for a variety of food allergies, not just peanuts. And we now offer early oral immunotherapy for children ages 3 and younger. It’s important that OIT is done under the careful supervision of your child’s pediatric allergist.
OIT for peanut allergies
For peanut allergies, we can use Palforzia™, an FDA-approved peanut allergen oral powder on children between ages 4 and 17, if we decide they’re eligible.
We’ll have them start taking peanut protein powder in tiny doses. We’ll then gradually increase the amount over time to build tolerance and minimize the risk of life-threatening complications like anaphylaxis.
Our food allergy experts are certified Palforzia providers, meaning we maintain high safety standards throughout treatment. On the rare occasions that anaphylaxis occurs, we detect early signs and work quickly to stop it with injectable epinephrine.
Your child will take their first dose and any doses where we increase the amount of powder (up-dosing) at their pediatric provider’s office. This lets their provider carefully watch how your child responds to their first dose and future dosing increases.
Your child will continue to take each dosage level of peanut powder at home, between up-dosing appointments. That’s why it’s important to always have injectable epinephrine available at home. You’ll need to keep an eye on your child for any reaction symptoms.
It can take years for your child to achieve peanut desensitization using oral immunotherapy. Regular follow-up visits are necessary to monitor progress and tailor your child’s care. And it’s important that they continue to avoid peanuts in their diets because oral immunotherapy doesn’t cure the allergy.
Sublingual immunotherapy
Your child’s provider will put small doses (drops) of the allergic protein (at amounts too low to cause a reaction) under your child’s tongue daily. Your child will need to be able to hold the drops under their tongue for two minutes, then swallow. This therapy can help your child build a tolerance without having an allergic reaction.
Taking the Next Step
Everyday encounters with foods that trigger allergic reactions don’t have to define your child’s life. Or your family’s. Oral immunotherapy doesn’t cure allergies. But it can help your child become desensitized — so you don’t have to worry so much about accidental exposure to a trigger food (like peanuts) at school, birthday parties or summer camp. At Cleveland Clinic Children’s, our providers will walk your family through what to expect from OIT and see if it’s a good option for your child. If it is, they might be able to enjoy a little more freedom — and you might be able to feel a little more at peace.
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Getting an appointment with Cleveland Clinic Children’s oral immunotherapy experts is easy. We’re here to help your child get the care they need.
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