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Invention Disclosures
Today’s medical innovations are shaping the future of healthcare. Cleveland Clinic Innovations accelerates that progress, transforming ideas from the brightest minds in medicine into patient-centered solutions.
As the commercialization engine of one of the world’s leading research hospitals, we connect discoveries that address healthcare’s greatest unmet needs to business opportunities that can bring them to market. Our team licenses medical technologies, launches healthcare startups and builds strategic collaborations with industry partners, with the goal of bringing therapies and products to patients that improve outcomes, reduce costs and expand access to care.
For industry partners, we’re the gateway into Cleveland Clinic’s integrated healthcare ecosystem. Innovators who share our goals can scale and validate emerging technologies alongside renowned Cleveland Clinic clinicians and researchers.
Our portfolio spans medical devices, therapeutics, diagnostics, digital health and AI-driven healthcare solutions, developed within Cleveland Clinic and grounded in clinical validation.
Tap into our pipeline of 600+ licensable technologies across medical domains including cardiology, neurology, endo-robotics and more. Every technology in our portfolio is vetted for patent potential and real-world commercial fit.
We welcome investors and partners to explore our portfolio and discover opportunities to invest in the future of healthcare. Our 28+ portfolio companies showcase our commitment to make the latest scientific discoveries available to patients around the world.
Our team partners with Cleveland Clinic caregivers to assess, protect, build and market promising ideas and transforms them into commercialized products that improve patient care.
Together, we are reimagining the health journey by developing and commercializing technologies that streamline hospital operations, reduce costs and connect patients to specific therapies.
Invention Disclosures
License Agreements
New Inventors
Current Portfolio Companies
Cleveland Clinic’s globally recognized ecosystem of research, discovery and unmatched clinical talent fuels our work to solve healthcare’s greatest challenges. Partners who share our vision can leverage the strengths of our vast research network and work alongside clinicians who care for diverse populations and take on some of the most complex cases. In collaboration, we can pressure test new platforms, validate clinical data and derisk products and therapies before they reach the market.
Cleveland Clinic’s 80,000+ caregivers are problem-solvers by nature, and innovation has always been central to our culture. Across specialties and global patient populations, they identify unmet needs and imagine better ways to solve them. We connect their promising ideas to the resources needed to bring them to market and, by extension, to patients worldwide. And, through co-development partnerships, our caregivers build healthcare solutions side-by-side with industry partners.
Within Innovations, our experts oversee each stage of the healthcare innovation and technology commercialization process. We match our expertise in intellectual property management, technology development, licensing and startup incubation to our partners' unique needs and offer individualized commercialization pathways to bring innovations to patients at scale.
In 2025, we reimagined what it means to partner with Cleveland Clinic Innovations and expanded the ways we bring healthcare innovations to patients at scale. In doing so, we saw 58 new license agreements and 207 new invention disclosures. We announced a strategic collaboration with Khosla Ventures, one of Silicon Valley’s leading investors in healthcare commercialization and technology – an example of how we’re strategically connecting outside innovation to our world-class ecosystem of research, discovery and clinical talent.
We are more than a tech transfer office. We are a medical innovations powerhouse. Cleveland Clinic Innovations is changing healthcare for patients around the world. Contact us to partner or learn more about what we do and why we do it.