Cleveland Clinic logo

GLP-1 Diet Guidance

GLP-1 agonists affect the way your body signals hunger and digests food. Combined, these changes help manage blood sugar levels and trigger weight loss. GLP-1s can also cause gastrointestinal (GI) side effects like nausea and constipation. So, it’s important to consider what foods you eat while taking this medication. That way, you can benefit from the wanted effects of your GLP-1 and minimize the unwanted ones.

The Gist of GLP-1s

When you take a GLP-1 agonist, food stays in your stomach longer. Because of this, certain foods can contribute more to the GI side effects, like spicy and high-fat foods. GLP-1s also reduce your appetite, so you end up eating less. But your body still needs a variety of nutrients to be healthy. You’ll want to make sure you’re getting these nutrients while eating less food.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

Foods To Choose When on a GLP-1

In general, nutritionally packed foods are helpful when taking a GLP-1. Reach for foods like:

  • Fruits and vegetables like leafy greens, apples and tomatoes
  • Lean protein sources like fish, chicken, tofu and beans
  • Whole grains like oats, quinoa and farro

Two nutrients to keep at the top of your mind — and on your plate — are protein and fiber. They both help keep you feeling full longer and stabilize blood sugar.

Protein also keeps your body from losing muscle instead of fat. And fiber can help combat constipation that a GLP-1 can cause.

Foods To Limit or Avoid

Certain foods can make GLP-1 side effects worse. Every body is different, so it may take time to figure out what triggers symptoms for you. In general, try to limit or avoid:

  • Sources of added sugar like juice, soda, candy and desserts
  • Refined carbs like white bread, crackers and white rice
  • Processed foods like packaged snacks
  • High-fat foods like pizza and fried chicken
  • Spicy foods like hot sauce and hot peppers

It Takes Time — and a Village

Adjusting to a GLP-1 while changing your diet may be overwhelming. You don’t have to go through it alone. A registered dietitian can help you form an eating plan that’s unique to your needs. It may take time and a little trial and error. You can also reach out to others who are taking GLP-1s for recipes and advice. Lean on friends and family members, too — it can be fun to discover new favorite meals with loved ones.

Advertisement

Related Content

Older man getting a mammogram, with healthcare provider
August 13, 2026/Cancer Care & Prevention
Yes, Men Can Get Breast Cancer, Too

It’s much less common in men, but it can happen — so it’s important to recognize warning signs and symptoms

Healthcare provider showing a patient information on a medical tablet
August 13, 2026/Heart Health
Myocarditis vs. Pericarditis: What You Should Know

These conditions involve inflammation in different areas of your heart, leading to differences in symptoms and treatments

Older man speaking during a support group meeting
August 13, 2026/Cancer Care & Prevention
Caring for Your Mental Health With Advanced Prostate Cancer

Anxiety, grief and anger are common after an advanced prostate cancer diagnosis — support and healthy coping strategies can help

Person emerging from the water sea side
August 12, 2026/Skin Care & Beauty
Is Saltwater Good for Your Hair and Skin?

Excessive exposure to saltwater can dehydrate skin and hair, despite having a few benefits

Halved lemons on cutting board next to glass bowl of lemon juice
August 12, 2026/Nutrition
Is Lemon Juice Good for You? 6 Health Benefits To Know

This bright citrus juice is packed with vitamin C and other nutrients that support your health

Person rinsing off in outdoor shower after swimming
August 12, 2026/Skin Care & Beauty
Protect Your Hair From Chlorine the Next Time You Go Swimming

A fresh water rinse before and after swimming can go a long way