Steven Nissen, M.D.
| Appointed: |
1992 |
| Gender: |
Male |
| Languages: |
English |
Cardiovascular Medicine
Director, Joseph J. Jacobs Center for Thrombosis and Vascular Biology
Molecular Cardiology
Biographical Sketch
Steven Nissen, MD, is the Chairman of the Robert and Suzanne Tomsich Department of Cardiovascular Medicine located on the main campus of Cleveland Clinic. He was appointed in 2006. Prior to this, he served nine years as Vice-Chairman of the Department of Cardiology and five years as Medical Director of the Cleveland Clinic Cardiovascular Coordinating Center (C5), an organization that directs multicenter clinical trials.
Dr. Nissen’s research during the last two decades has focused on the application of intravascular ultrasound (IVUS) imaging for the assessment of progression and regression of coronary atherosclerosis. He has served as International Principal Investigator for several large IVUS multi-center atherosclerosis trials.
Contributions to scientific literature include approximately 270 journal articles with a respectable number of manuscripts in NEJM, Circulation, and JAMA, in addition to 60 book chapters and electronic publishings. In recent years, he has also written on the subject of drug safety and was the author of manuscripts highlighting concerns about the COX-2 inhibitors, muraglitazar and rosiglitazone.
Other contributions include current service as editor of Current Cardiology Report, and senior consulting editor to the Journal of the American College of Cardiology.
Dr. Nissen's national positions include:
One-year term as president of the American College of Cardiology (ACC) from March 2006 to March 2007. He currently serves as a member of the Executive Committee and the Board of Trustees of the ACC. He has served several terms on the Programming Committee for ACC Annual Scientific Sessions.
Dr. Nissen served as a member of the CardioRenal Advisory Panel of Food and Drug Administration (FDA) for five years, and as chairman of the final year of his membership. He continues to serve as a periodic advisor to several FDA committees as a Special Government Employee.
Dr. Nissen is a frequent lecturer before national and international meetings. He has served as visiting professor, or provided Grand Rounds, at nearly 100 institutions.
As a physician/scientist, Dr. Nissen consults for many pharmaceutical companies on the development of new therapies for cardiovascular disease, but maintains his longstanding personal policy of requiring companies to donate all related honoraria directly to charity.
Dr. Nissen is also known for his role in public policy discussions, particularly in the area of drug safety. He has testified in both the Senate and the House of Representatives on this issue as well as the need to reform the Food and Drug Administration (FDA).
Dr. Nissen was selected for the Outstanding Scientist Award by the Cleveland Clinic in 2004.
He received the Outstanding Teacher Award, presented by the Fellows of Cardiovascular Medicine, on three occasions.
Dr. Nissen also received Award for Outstanding Contributions to Cardiovascular Research from the Gill Heart Institute of the University of Kentucky in 2004.
In 2007, Dr. Steven Nissen was named by TIME Magazine as "one of the 100 most influential people in the world".
Dr. Nissen was also named in 2007 by SmartMoney Magazine as one of the "country’s 30 most powerful forces in business and finance."
Dr. Nissen earned his medical degree from the University of Michigan School of Medicine in Ann Arbor. He completed Internal Medicine internship and residency at the University of California, Davis in Sacramento, and Cardiology Fellowship at the University of Kentucky Medical Center in Lexington. Dr. Nissen's early career years were spent at the University of Kentucky College of Medicine achieving a rank of Associate Professor.
Professional Highlights
- Principal Investigator, Global Cardiovascular Innovations Center, Cleveland Clinic, 2006
- Director, Joseph J. Jacobs Center for Thrombosis and Vascular Biology, Cleveland Clinic
- Member, National Institutes of Health Level 1 Working Group on Clinical Trial Design National Heart, Lung, and Blood Institute (NIH), 2006
- National Government Service: Presently serves as Special Government Employee as periodic advisor to the U.S. Food and Drug Administration (FDA).
- Chairman, Cardiovascular Renal Drugs Advisory Committee, Department of Health and Human Resources, U.S. FDA, 2004 - 2005
- Member, Cardiovascular Renal Drugs Advisory Committee, Department of Health and Human Resources, U.S. FDA, 2000 - 2004
- Medical Director, Cleveland Clinic Cardiovascular Coordinating Center - an organization that directs multicentric clinical trials, 2001 - 2006
Education & Fellowships
| Medical School: | University of Michigan Medical School, Ann Arbor, MI |
|
| Internship: | University of California Davis Medical Center, Medical Internship, Sacramento, CA |
| Residency: | University of California Davis Medical Center, Internal Medicine, Sacramento, CA |
| Fellowship: | University of Kentucky Chandler Medical Center, Cardiology, Lexington, KY |
| Other Education: | (Undergraduate) University of Michigan, Ann Arbor, MI |
Additional Training
- Intensive Care Units Committee, University of Kentucky Medical Center, 1983-1992
- Aeromedical Patient Care for the University of Kentucky, 1987-1992
- Certification - Cardiovascular Medicine, American Board of Internal Medicine, 1983
- Certification - American Board of Internal Medicine, 1979
- Certification - National Board of Medical Examiners, 1979
Certifications
Cardiovascular Disease
Internal Medicine
Specialty Interests
Intravascular ultrasound, digital angiography and computer image processing, coronary intensive care.
Innovations & Patents
- Dr. Steven Nissen was one of the pioneers in the development of intravascular ultrasound (IVUS) and his research during the last two decades has focused on this imaging technique. Specifically, he developed the methods used to employ IVUS in the assessment of the progression and regression of coronary atherosclerosis. He has served as principal investigator for 6 major trials using IVUS to assess coronary disease and is currently conducting several additional atherosclerosis studies.
- Co-chairman, American College of Cardiology and the European Society of Cardiology International Writing Group to develop an Expert Consensus Document on Standards for the Acquisition, Measurement, and Reporting of Intravascular Ultrasound Studies, 1999-2001
- Member, National Joint Committee of the American College of Cardiology and the American Heart Association to revise 1990 Coronary Angiography Guidelines, 1995-2000
- Appointed committee member in the development of CD-ROM Version of the American College of Cardiology Self-Assessment Program (ACC-SAP), 1994-1996
- Co-chairman Joint Committees of the American College of Cardiology and National Electronics Manufacturers Association for Digital Imaging and Communication for Medicine (DICOM) Working Group I, Task Force to Develop Standards for Digital Image Archiving Devices for Cardiac Catheterization Laboratories, 1992-2000
Awards & Honors
- "100 Most Influential People in the World," TIME Magazine, 2007
- "Country’s 30 Most Powerful Forces in Business and Finance," Smart Money, 2007
- President, American College of Cardiology, a 34,000 member, non-profit, professional medical society, whose mission is to advocate for quality cardiovascular care - through education, research promotion, development and application of standards and guidelines - and to influence health care policy, March 2006 thru March 2007
- Honorary Member of the Japanese College of Cardiology (JCC), 2007
- Award for Outstanding Contributions to Cardiovascular Research from the Gill Heart Institute of the University of Kentucky, 2004
- Outstanding Scientist Award by the Cleveland Clinic, 2004
- A number of additional honors and recognitions have been bestowed on Dr. Nissen; on three occasions, he received the Outstanding Teacher Award presented by the Fellows of Cardiovascular Medicine at Cleveland Clinic, 2004, 1998, 1994
Professional Memberships
- Master of the American College of Cardiology (ACC), March 2006
- Fellow of the American College of Cardiology, 1987 - 2006
- ACC activities include serving as member Board of Trustees twice as well as chairman, co-chairman, member, ex-officio representative to more than thirty committees, task forces, working and writing groups.
- Member, Professional Medical Associations (PMA), 2007
- Member, Association of American Physicians (AAP), 2007
- Member, Association of Professors of Cardiology (APC), 2006-present
- Editor, Current Cardiology Reports, 2006 - present
- Senior Consulting Editor, Journal of the American College of Cardiology, 2002 - present
- Dr. Nissen's contributions to scientific literature includes being member of 12 Editorial Boards for peer review medical journals, as well as providing service as Reviewer to 23 additional Editorial Boards, 1989 - present
Specializes in Diseases and Conditions
Specializes in Services
Industry Relationships
Cleveland Clinic physicians and scientists report if they have any collaborations with the pharmaceutical or medical device industries as part of the Cleveland Clinic’s procedures. The Cleveland Clinic publicly discloses payments to its physicians and scientists for speaking and consulting of $5,000 or more per year, and any equity, royalties, and fiduciary relationships in companies with which they collaborate. In publicly disclosing this information, the Cleveland Clinic tries to provide information as accurately as possible about its doctors’ connections with industry and those of their immediate family members. As of 12/8/2008, Dr. Nissen has reported no financial relationship with industry that is applicable to this listing. Patients should feel free to contact their doctor about relationships with industry and how the relationships are overseen by the Cleveland Clinic. To learn more about the Cleveland Clinic’s policies on collaborations with industry and innovation management, go to our
Integrity in Innovation page.
Dr. Nissen reports that he has consulted for the following companies and has them donate all honoraria or consulting fees directly to non-profit organizations so that he receives neither income nor a tax deduction.
- Abbott
- AstraZeneca
- Atherogenics
- Boehringer Ingelheim
- Daiichi-Sankyo
- Eisai Inc.
- Eli Lilly
- Entity
- Forbes Medi-tech
- GlaxoSmithKline
- Haptogard
- Hoffman-LaRoche
- Isis Pharmaceuticals
- Kemia
- Kos Pharmaceuticals
- Kowa
- Lipid Sciences
- Novartis
- Novo-Nordisk
- Pfizer
- Protevia
- Sanofi Aventis
- Sumitomo
- Takeda
- Vascular Biogenics
- Vasogenix
- Wyeth
- Xintria
( † Disclaimer: This search is powered by PubMed, a service of the U.S.
National Library of Medicine. PubMed is a third-party website with no
affiliation with Cleveland Clinic.)
