Cancer Advances
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Featured Episode
Exploring the Microbiome in Young-Onset Colorectal Cancer
Young-onset colorectal cancer is becoming more common, and the microbiome could be playing a role in the increase of cases. Alok Khorana, MD, Director of the Gastrointestinal Malignancies Program at Cleveland Clinic Cancer Institute, joins the Cancer Advances Podcast to discuss this issue. Listen as Dr. Khorana highlights his research on the link between changes in the microbiome and the development and progression of colorectal cancer in younger patients. He also discusses the ongoing metabolomic analysis and investigations.
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May 9, 2024
Advancing Organ Preservation in Rectal Cancer
The Cancer Advances podcast is joined by colorectal surgeons, I. Emre Gorgun, MD, Vice Chair of the Department of Colorectal Surgery, and Joshua Sommovilla, MD, Director of the Colon Cancer Tumor Board, to talk about organ preservation in rectal cancer treatment. Listen as they discuss the rising use of neoadjuvant therapy to shrink tumors before surgery, endoluminal procedures, and the importance of close surveillance and follow-ups for patients.
Play NowMay 2, 2024
Trailblazing Urothelial Cancer Treatments: Enfortumab Vedotin & Pembrolizumab
Shilpa Gupta, MD, Director of the Genitourinary Oncology Program at Cleveland Clinic Cancer Institute, provides an overview of the clinical trial of enfortumab vedotin and pembrolizumab in untreated advanced urothelial cancer. Listen as Dr. Gupta talks about the exciting results of the trial, which showed that the combination therapy was effective for both cisplatin-eligible and cisplatin-ineligible patients. She also highlights the future studies that are being conducted to explore the use of the therapy in the neoadjuvant setting.
Play NowApril 18, 2024
Beyond Chemotherapy: Advancements in ALL Treatment
Anjali Advani, MD, Director of the Inpatient Leukemia Unit at Cleveland Clinic, joins the Cancer Advances Podcast to talk about the innovations in acute lymphoblastic leukemia (ALL). While chemotherapy has traditionally been the go-to treatment, advancements like blinatumomab and CAR-T cell therapy are reshaping care. Listen as Dr. Advani discusses the challenges and considerations in choosing these therapies, CAR-T re-challenge potential, and the future directions in ALL treatments.
Play NowApril 11, 2024
In the Pursuit of Parenthood: Pregnancy, Breast Cancer, and BRCA Mutations
Halle Moore, MD, Director of Breast Medical Oncology at Cleveland Clinic, joins the Cancer Advances Podcast to explore the safety of pregnancy after breast cancer with BRCA mutations. In the episode, Dr. Moore emphasizes the importance of early conversations regarding reproductive goals and available fertility preservation strategies for breast cancer patients while maintaining an effective cancer treatment. Despite limited data on this topic, Dr. Moore highlights positive outcomes observed in retrospective studies.
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