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Cleveland Clinic Physical Medicine & Rehab

Clinical Studies and Research

 
 
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Research within Physical Medicine & Rehabilitation is focused on understanding the mechanisms underlying the various conditions treated by our clinicians as well as developing innovative treatment strategies to accelerate and improve clinical outcomes for our patients.

We publish our findings in prestigious journals and translate our findings into practice for our patients. 

Researchers in the department are funded by:

  • National Institute of Health
  • Department of Defense
  • National Science Foundation
  • National Research Council 
  • Various Corporate Sponsors
  • Departmental funds
Research

Past Research Projects have focused on chronic fatigue, spinal cord injury, effect of mental imagery on voluntary muscle strength and the development of new concepts in wheelchair securements and occupant restraints for the wheelchair-using public.

Current Research Projects are investigating novel treatment protocols for accelerating functional recovery in stroke patients, production of cough in spinal cord injury patients, mechanisms underlying cancer-related fatigue, developing and evaluating new products for improving quality of life for patients suffering from back pain and coccygodynia.

Research conducted by our clinicians and research staff in collaboration with other clinical departments and external institutions has culminated in numerous publications in peer-reviewed scientific journals, presentations in national and international conferences, patents and commercial products.

Innovations / Patents
  • Reger SI, Neth DC and McGovern TF. Computer Aided Prescription of Specialized Seats for Wheelchairs or Other Body Supports. U.S. Patent Number 4,890,235 (20 claims) Received: December 26, 1989
  • U.S. Patent Number 4,972,351 (20 further claims) Received: November 20, 1990
  • Reger SI, Cardona E, Adams TC and Takacs J: Mobility Aid Securement System for Vehicles U.S. Patent Number 6,899,497 Received: May 31, 2005
  • Reger, S.I., Navarro R.: Patient Support Apparatus Having an Air Cell Grid and Associated Method. US Patent Application No: 10/839,002 Filed by CCF: May 5, 2004.
  • Reger, S.I., Snyder E., Papay F., Sahgal V.: Head Support for Pressure Relief. CCF Innovation Disclosure No: 02480 Submitted August 2002 Approved for CCF internal use September 2004.
  • Reger, S.I., Ranganathan VK, Butler, R. Prediction of Clinical Outcome Using Large Array Surface Myoelectric Potential. US Provisional Patent Application filed by CCF: October 2, 2006.
Selected peer-reviewed publications
  • Chae J, Jedlicka L. Subacromial corticosteroid injection for poststroke shoulder pain: an exploratory prospective case series. Arch Phys Med Rehabil 2009 Mar;90(3):501-506.
  • Daly JJ, Hrovat K, Pundik S, Sunshine J, Yue G. fMRI methods for proximal upper limb joint motor testing and identification of undesired mirror movement after stroke. J Neurosci Methods 2008 Oct 30;175(1):133-142.
  • Frost F. Stroke. In: Walsh D, ed. Palliative Medicine Philadelphia, PA: Saunders/Elsevier; 2009:1040-1044.
  • Frost FS, Mukkamala S, Covington E. Self-inflicted finger injury in individuals with spinal cord injury: an analysis of 5 cases. J Spinal Cord Med 2008;31(1):109-116.
  • Hou JY, Reger SI, Sahgal V. Durable medical equipment. In: Walsh D, ed. Palliative Medicine Philadelphia, PA: Saunders/Elsevier; 2009:565-573.
  • Khoshknabi DS, Davis MP, Ranganathan VK, Siemionow V, Walsh D, Kirkova J, Yue GH. Combining objective and subjective outcomes in cancer-related fatigue: illustrations from a single case report. J Palliat Med 2008 Jul;11(6):829-833.
  • Landers SH. The other medical home. JAMA 2009 Jan 7;301(1):97-99.
  • Liang HW, Landers SH. Who receives house calls? J Am Geriatr Soc 2008 Aug;56(8):1581-1582.
  • Lin VWH, Juraschek SP, Xu L, Jones D, Turek J. California regional registered nurse workforce forecast. Nurs Econ 2008 Mar;26(2):85-105,121.
  • Lin VWH, Deng X, Lee YS, Hsiao IN. Stimulation of the expiratory muscles using microstimulators. IEEE Trans Neural Syst Rehabil Eng 2008 Aug;16(4):416-420.
  • Podichetty VK, Reddy A. Acupuncture, transcutaneous electrical nerve stimulation, and topical analgesics. In: Walsh D, ed. Palliative Medicine. Philadelphia, PA: Saunders/Elsevier; 2009:1398-1404.
  • Rosenstein L, Ridgel AL, Thota A, Samame B, Alberts JL. Effects of combined robotic therapy and repetitive-task practice on upper-extremity function in a patient with chronic stroke. Am J Occup Ther 2008 Jan;62(1):28-35.
  • Schilling DL, Dixon P. Occupational and physical therapy. In: Walsh D, ed. Palliative Med Philadelphia, PA: Saunders/Elsevier; 2009:277-278.
  • Shah RR, Haghpanah S, Elovic EP, Flanagan SR, Behnegar A, Nguyen V, Page SJ, Fang ZP, Chae J. MRI findings in the painful poststroke shoulder. Stroke 2008 Jun;39(6):1808-1813.
  • Wang XF, Yang Q, Fan Z, Sun CK, Yue GH. Assessing time-dependent association between scalp EEG and muscle activation: A functional random-effects model approach. J Neurosci Methods 2009 Feb 15;177(1):232-240.
  • Yang Q, Fang Y, Sun CK, Siemionow V, Ranganathan VK, Khoshknabi D, Davis MP, Walsh D, Sahgal V, Yue GH. Weakening of functional corticomuscular coupling during muscle fatigue. Brain Res 2009 Jan 23;1250:101-112.
  • Zhang L, Butler AJ, Sun CK, Sahgal V, Wittenberg GF, Yue GH. Fractal dimension assessment of brain white matter structural complexity post stroke in relation to upper-extremity motor function. Brain Res 2008 Sep 4;1228:229-240.