Gastrointestinal Pathology Consultative Group
Specializing in gastrointestinal, hepatic, and pancreaticobiliary pathology. The gastrointestinal pathology consultative service of Cleveland Clinic's Reference Laboratory offers a complete gastrointestinal disease management program, including diagnosis, therapeutic monitoring, and disease tracking for neoplastic and non-neoplastic digestive diseases.
Experience and Expertise
Our faculty members are subspecialty trained in gastrointestinal, hepatic, and pancreaticobiliary pathology with years of subspecialty practice in a challenging multidisciplinary academic environment. Their interests cover the range of diseases, including Barrett’s esophagus; inflammatory bowel disease; cancer and precancerous conditions; mesenchymal lesions; hepatic and pancreatic diseases; and transplantation pathology.
This service attracts consultations from across the United States and internationally, provides expert diagnosis and second opinions on more than 4,000 cases annually, including the most rare and complex pathology in this field. We also provide pathologic interpretations for numerous large NIH and industry-funded gastrointestinal research trials each year and process more than 40,000 gastrointestinal, hepatic, and pancreaticobiliary cases annually in our clinical practice at Cleveland Clinic.
Recognized for Excellence
U.S. News & World Report has named Cleveland Clinic's Department of Gastroenterology among the top three departments in the country every year since 1998. The expertise of our gastrointestinal pathologists, who work closely with the clinicians in diagnosis and treatment planning, plays a significant role in this accomplishment. Our work in pathology is greatly enhanced by our access to the renowned clinical expertise at Cleveland Clinic.
National and International Reputation
Cleveland Clinic gastrointestinal pathologists have attained leadership positions in the premier professional organizations in the field, are welcomed as distinguished guest lecturers and speakers at respected conferences around the world, and publish extensively in leading medical journals.
In addition to conventional techniques for evaluation of gastrointestinal, hepatic, and pancreaticobiliary specimens, our laboratory offers an extensive in house immunohistochemical test menu and molecular pathology testing, allowing for accurate diagnoses and prognosis of gastrointestinal neoplasia.
- Mismatch repair protein expression by immunohistochemistry (hMLH1, hMSH2, hMSH6 and PMS2)
- Microsatellite instability (MSI) evaluated by PCR (molecular)
- KRAS codon 12/13 mutation (Sanger sequencing molecular)
- BRAF V600 mutation (Sanger sequencing molecular)
- HER 2 immunohistochemistry and fluorescence in situ hybridization (FISH) for gastric and GE junction carcinoma
Our Service Commitment
Cleveland Clinic's Reference Laboratory is committed to meeting the needs of referring physicians by providing expert diagnosis with rapid turnaround. Most diagnostic reports and detailed consultative reports are provided by fax within two to three days from the time that specimens are received. More complex cases or those that require additional testing may require additional days to complete.
Telephone consultation with a Cleveland Clinic gastrointestinal pathologist is available on all cases.
To arrange a consult, call Client Services locally at 216.444.5755 or toll-free 800.628.6816.