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William Stewart, MD


William Stewart, MD
Department: Cardiovascular Medicine
Location: Cleveland Clinic Main Campus
Mail Code J1-5
9500 Euclid Avenue
Cleveland, OH 44195
Type of Doctor:
Adults Only

Biographical Sketch

William James Stewart, M.D., has been a staff physician in the Department of Cardiovascular Medicine at The Cleveland Clinic since 1984. He is a Fellow of the American College of Cardiology and the American Society of Echocardiography, giving him the titles of F.A.C.C. and F.A.S.E. Dr. Stewart is board certified in Cardiovascular Disease, Internal Medicine and Echocardiography. His specialty interests include valvular heart disease, mitral valve repair, aortic valve repair, clinical cardiology, Doppler echocardiography, hemodynamic research, transesophageal echocardiography (TEE), intraoperative echocardiography, and echo guidance of transcatheter (percutaneous) valve procedures.

A native of Cleveland and graduate of Brush High School (Lyndhurst), he did undergraduate studies at Harvard, graduating Cum Laude. He received his medical degree from the University of Cincinnati, and did his Internal Medicine residency training at the University of Michigan. After a cardiology fellowship at Boston University Medical Center; he did a two year Cardiac Imaging Research and Clinical fellowship at Harvard Med School's Massachusetts General Hospital.

An expert on heart valve problems, William J. Stewart, M.D. has helped thousands decide on the optimum timing for surgery/repair of valve disease; including regurgitation or stenosis, of the mitral and/or the aortic valve. He is a reviewer for Circulation, Journal of the American College of Cardiology, Journal of the American Society of Echocardiography, Heart, and Echocardiography.

Dr. Stewart is also an expert in cardiac imaging, and has written board questions for the National Board of Echocardiography, the certifying body for fellowship in this field. For the American Society of Echocardiography (ASE), he has served one term as Treasurer, and twice on the Board of Directors, and many years on the Intraoperative Echocardiography Council. He is on the writing committee for the Partner Trial studying Transcatheter Aortic Valve Replacement (TAVR) and coauthored the recently published guidelines for TEE.

Dr. William Stewart has published over 180 scientific articles in leading medical journals on his specialty interests and research. He has authored 35 chapters in medical textbooks, related mostly to treatment of valvular heart disease and its diagnosis with echocardiography.

As a Professor of Medicine (since 2008) on the faculty at Cleveland Clinic Lerner College of Medicine (CCLCM) of the Case Western Reserve University, he has been Director of the Cardiovascular Curriculum and the Cardio-Pulmonary Block for first year med students since prior to the inception of the school in 2004. He serves on the Basic Science Education Committee, and teaches seminars and clinical correlations to first and second year students. He received the Kaiser-Permanente Teaching Award for Basic Science Education, from CCLCM in 2007.

He has been named on the “Best Doctors” list, on a yearly basis since 1994, including “Best Doctors in America,” published by Castle Connolly, and others. Over a dozen times, he has been named as one of the “Best Doctors in Cleveland” by Cleveland Magazine.

Bill Stewart is highly involved in family life, with his wife, two grown children, and twin grandbabies. He is an avid exerciser, sailor, downhill skier, and amateur ornithologist. He is a musician and singer, serving weekly as worship leader for his local Christian church congregation, where he is also Senior Warden and on the vestry. He is the faculty advisor to the Cleveland Clinic chapter of the Christian Medical and Dental Association (CMDA) and serves the Northeast Ohio CMDA. He is a committed believer in Jesus Christ, and has been featured on television for his interests in the integration of medicine, faith, and spirituality. Dr. Stewart believes in the power of prayer, working together with scientific medicine, for healing illness.

Professional Highlights

  • Co-Investigator, Everest II Trial, of percutaneous edge-to-edge repair of mitral regurgitation
  • Co-Investigator, Partner Trial, of percutaneous aortic valve replacement
  • Co-Investigator, Revival Trial, of transcatheter aortic valve replacement using the per-apical approach
  • Co-Investigator, Post Coronary Artery Bypass Graft Clinical Trial (Post CABG Trial)
  • Cardiovascular Study Section, Institutional Review Board, Cleveland Clinic, 1987-1996

Education & Fellowships

Fellowship - Massachusetts General Hospital
Boston, MA USA
Fellowship - Boston Medical Center
Boston, MA USA
Residency - University of Michigan Health System
Internal Medicine
Ann Arbor, MI USA
Internship - University of Michigan Health System
Internal Medicine
Ann Arbor, MI USA
Medical School - University of Cincinnati College of Medicine
Cincinnati, OH USA
Undergraduate - Harvard University
Cambridge, MA USA


  • Internal Medicine
  • Internal Medicine- Cardiovascular Disease

Specialty Interests

Mitral and Aortic Valve Problems, Cardiac Valve Disease - Diagnosis and Therapy, Valve repair, Transesophageal and Transthoracic Echocardiography, Imaging for Transcatheter Interventions, Endocarditis, Pericardial Disease, Cardiovascular Imaging, Cardiac tumors.

Awards & Honors

  • Kaiser-Permanente Teaching Award for Basic Science Education, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, 2007
  • America’s Top Doctors, Castle Connolly Medical Ltd., New York (peer selection from nationwide survey of 200,000 doctors), 2001-2007 
  • Top Docs, Northern Ohio Live magazine, 2007
  • Best Doctors in America for Cleveland, Cleveland magazine, 1998, 2002-2006
  • Best Doctors in America, Consensus Support of Peers Survey Best Doctors, Inc. Woodward White Press, Aiken, S.C., 1994, 2005  
  • Guide to America’s Top Physicians, Consumers’ Research Council of America, Washington, D.C., 2004-2005 
  • Champion, Echo Jeopardy, American Society of Echocardiography, 15th Annual Scientific Sessions, San Diego, Calif., 2004 
  • The Best Doctors in the Midwest for Echocardiography, Survey of Medical Specialists, Woodward White Press, Aiken, S.C., 1998

Additional Training

Advanced Clinical and Research Fellow, Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., 1982-1984

Innovations & Patents

  • Intraoperative echocardiography
  • Transesophageal echocardiography
  • Understanding the mechanism of mitral regurgitation to enable mitral valve repair
  • Understanding the mechanism of aortic regurgitation to enable aortic valve repair
  • Echocardiography in transcatheter (percutaneous) repair for mitral regurgitation
  • Echocardiography in transcatheter (percutaneous) aortic valve replacement femoral or apical


  • Fellow, American Society of Echocardiography (FASE)
  • Fellow, American College of Cardiology (FACC)

Treatment & Services

Specialty in Diseases and Conditions

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 6/20/2016, Dr. Stewart has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers’ discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Languages Spoken

  • English

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