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Kathleen Berkner, PhD

Kathleen Berkner, Ph.D.

Appointed: 1993

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Kathleen Berkner, PhD
Department: Molecular Cardiology
Location: Cleveland Clinic Main Campus
Mail Code NB50
9500 Euclid Avenue
Cleveland, OH 44195
Kathleen Berkner, PhD
Department: Cardiovascular Medicine
Location: Cleveland Clinic Main Campus
Mail Code NB50
9500 Euclid Avenue
Cleveland, OH 44195
Type of Doctor:

Biographical Sketch

Kathleen Berkner, PhD, is a member of the Associate Staff of the Department of Molecular Cardiology in the Cleveland Clinic Lerner Research Institute. She is also a member of the Associate Staff of the Center for Thrombosis and Vascular Biology, and she has a Joint Appointment in the Department of Cardiology.

Dr. Berkner also has a teaching role. She is a CCF Associate Professor in the Department of Chemistry at Cleveland State University in Cleveland, Ohio.

Education & Fellowships

Doctorate - University of Michigan
Ann Arbor, MI USA
Undergraduate - University of Minnesota
Minneapolis, MN USA
Fellowship - Massachusetts Institute of Technology
Cambridge, MA USA
Fellowship - Baptist Memorial Hospital, Collierville
Memphis, TN USA

Specialty Interests

regulated secretion and post-translational modification of vitamin k-dependent proteins involved in hemostasis

Awards & Honors

  • Structure-Function Analysis of the Gamma-Carboxylase, Principal Investigator: Kathleen L. Berkner, PhD, National Heart, Lung and Blood Institute, NIH RO1 1997-2010 HL55666
  • Vitamin K Oxidoreductase: Function and Physiology, Principal Investigator: Kathleen L. Berkner, PhD, National Heart, Lung and Blood Institute, NIH RO1 2008-2013 HL81093

Additional Training

  • University of Michigan, PhD, 1977
  • Massachusetts Institute of Technology, Postdoctoral Fellow, 1978-1983

Innovations & Patents

Led the team that generated Novoseven as a hemostatic device and awarded several relevant patents


  • American Heart Association
  • International Society of Thrombosis and Haemostasis
  • The Protein Society
  • American Society for Cell Biology

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 3/3/2016, Dr. Berkner has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers’ discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Languages Spoken

  • English