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John Bartholomew, MD


John Bartholomew, MD
Department: Vascular Medicine
Location: Cleveland Clinic Main Campus
Mail Code J3-5
9500 Euclid Avenue
Cleveland, OH 44195
John Bartholomew, MD
Department: Cardiovascular Medicine
Location: Strongsville Family Health Center
Mail Code J3-5
16761 S Park Center
Strongsville, OH 44136
Type of Doctor:
Adults Only

Biographical Sketch

John Bartholomew, M.D. is Section Head of Vascular Medicine, Director of the Thrombosis Center and a staff physician in the Sydell and Arnold Miller Family Heart & Vascular Institute. He has a joint appointment to the Department of Hematology/Oncology. He is board-certified as a Diplomat of the American Board of Internal Medicine and the American Board of Vascular Medicine. He is a Professor of Medicine for the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University.

Dr. Bartholomew's specialty interests include clotting disorders (acquired and inherited), such as heparin-induced thrombocytopenia, antiphospholipid syndrome, thrombosis in cancer patients, protein C and S deficiencies, antithrombin deficiency and prothrombin gene mutation and Factor V Leiden, as well as elevated Factor VIII and homocysteine levels. In addition, Dr. Bartholomew's other clinical interests include peripheral arterial disease, the swollen limb including lymphedema, lipedema, thromboembolism (deep vein thrombosis and pulmonary embolism), leg ulcers and varicose and spider veins that he treats with sclerotherapy.

He did his undergraduate work at Central Michigan University. He received his medical degree from the Autonomous Universidad De Guadalajara, in Guadalajara, Jalisco, Mexico. He completed his internship and residency at Maryland General Hospital in Baltimore, where he was Chief Resident. He was awarded a fellowship by the Johns Hopkins Hospital and appointed Senior Clinical Fellow in the Division of Hematology. While at Johns Hopkins, he received the William Bell Award for Patient Care.

Prior to joining the Cleveland Clinic in 1989, Dr. Bartholomew was the Assistant Director of Internal Medicine Education at St. Joseph Hospital at Michigan State University, where he was given the Instructor of the Year Award for the Family Practice Residency Program. He also served as Director of the Eastern Michigan Hemophilia Center.

Dr. Bartholomew is the Medical Director of the Pharmacy managed Anticoagulation program, as well as Director of the Vascular Medicine Section’s Coumadin Clinic. In 2003, Dr. Bartholomew was part of the clinical faculty for the Joint Commission Resources, Inc., for the Joint Commission on Accreditation of Hospital Organizations (JCAHO). He has also been a member of the Deep Vein Thrombosis Steering Committee for the National Quality Forum, which sets the national standards for the care of patients with Deep Vein Thrombosis and Pulmonary Embolism. He currently serves as the Director of the Cleveland Clinic Health Systems efforts to prevent and treat deep vein thrombosis and pulmonary embolism.

Dr. Bartholomew was voted one of Cleveland's Best Doctor's by Cleveland Magazine from 2006 through 2011 and in 2004, 2002, 2001 and 1998. In 2001, he was named Teacher of the Year by Cleveland Clinic’s Department of Vascular Medicine.

He has published numerous articles and abstracts in professional scientific journals including the Annals of Internal Medicine, Transfusion, Cardiovascular Surgery, Circulation, the Cleveland Clinic Journal of Medicine, Chest, Archives of Internal Medicine, Journal of Pediatrics, and Vascular Medicine on topics related to smokeless tobacco and cardiovascular risk, peripheral artery disease, pulmonary embolism, and heparin-induced thrombocytopenia and deep vein thrombosis, among others. He has authored more than 40 chapters in medical textbooks related to atheromatous embolization, stasis leg ulcers, hypercoagulable states, heparin-induced thrombocytopenia, and peripheral arterial disease.

Dr. Bartholomew has been an invited speaker at workshops, symposiums and conferences on the diagnosis and treatment of deep vein and pulmonary embolism, peripheral arterial disease and the diagnosis and management of patients with hypercoagulable states and the diagnosis and treatment of heparin-induced thrombocytopenia.

He is a fellow of the Society for Vascular Medicine, a fellow of the American College of Cardiology, a fellow of the International Academy of Clinical and Applied Thrombosis and Hemostasis. He is a member of the American College of Physicians, the Johns Hopkins Medical and Surgical Society, the American Society of Hematology and the International Society of Thrombosis and Hemostasis.

Education & Fellowships

Fellowship - Johns Hopkins Hospital
Baltimore, MD USA
Residency - Maryland General Hospital
Internal Medicine
Baltimore, MD USA
Internship - Maryland General Hospital
Fifth Pathway
Baltimore, MD USA
Medical School - Universidad Autonoma De Guadalajara
Guadalajara, Jalisco Mexico
Undergraduate - Central Michigan University
Mt. Pleasant, MI USA


  • Internal Medicine
  • American Board of Vascular Medicine

Specialty Interests

Adverse effects anticoagulants, blood clots, hypercoagulable states, deep vein thrombosis, pulmonary embolism, general vascular medicine, peripheral artery disease, thrombolytic therapy

Awards & Honors

  • Voted one of Cleveland's Best Doctors by Cleveland Magazine, 1998 
  • Voted one of Cleveland's Best Doctors by Cleveland Magazine, 2001
  • Voted one of Cleveland's Best Doctors by Cleveland Magazine, 2002
  • Voted one of Cleveland's Best Doctors by Cleveland Magazine, 2004
  • Voted one of Cleveland's Best Doctors by Cleveland Magazine, 2006
  • Voted one of Cleveland's Best Doctors by Cleveland Magazine, 2007
  • Voted one of Cleveland's Best Doctors by Cleveland Magazine, 2008
  • Voted one of Cleveland's Best Doctors by Cleveland Magazine, 2009
  • Voted one of Cleveland's Best Doctors by Cleveland Magazine, 2010
  • Voted one of Cleveland's Best Doctors by Cleveland Magazine, 2011


  • American College of Cardiology
  • Society of Vascular Medicine and Biology
  • International Academy of Clinical and Applied Thrombosis and Hemostasis
  • American College of Physicians
  • Johns Hopkins Medical and Surgical Society

Treatment & Services

Specialty in Diseases and Conditions

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. The Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, the Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 6/26/2014, Dr. Bartholomew has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by the Cleveland Clinic. To learn more about the Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Royalty Payments. Dr. Bartholomew receives or has the right to receive royalty payments for inventions or discoveries commercialized through the companies shown below:

  • FlexLife Health, Inc. (Financial Interest is donated)

Right to Future Distribution of Cleveland Clinic Financial Interest. Dr. Bartholomew may receive future financial benefits from the Cleveland Clinic for inventions or discoveries commercialized through the companies shown below:

  • FlexLife Health, Inc. (Financial Interest is donated)

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers’ discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Languages Spoken

  • English