John Bartholomew, MD


4.9 out of 5
90 Patient Satisfaction Ratings 6 Comments
John Bartholomew, MD
Department: Vascular Medicine
Section Head
Location: Cleveland Clinic Main Campus
Mail Code J3-5
9500 Euclid Avenue
Cleveland, OH 44195
John Bartholomew, MD
Department: Cardiovascular Medicine
Location: Strongsville Family Health Center
Mail Code J3-5
16761 S Park Center
Strongsville, OH 44136
Type of Doctor:
Adults Only

Biographical Sketch

John R. Bartholomew, MD, is Section Head of Vascular Medicine, Director of the Thrombosis Center and a staff physician in the Sydell and Arnold Miller Family Heart & Vascular Institute at Cleveland Clinic. He has a joint appointment to the Department of Hematology/Oncology. Dr. Bartholomew is board-certified as a Diplomat of the American Board of Internal Medicine and the American Board of Vascular Medicine. He is a Professor of Medicine for the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University.

Specialty/Clinical interests: New oral anticoagulants, adverse effects of anticoagulants, heparin-induced thrombocytopenia, blood clots, hypercoagulable states (thrombophilia), deep vein thrombosis (DVT), pulmonary embolism, thrombosis in unusual locations, inferior vena cava filters, general vascular medicine, peripheral arterial disease, unusual vascular disorders including erythromelalgia, pernio, lymphedema and lipedema.

Number of Procedures Performed:  Throughout his career, Dr. Bartholomew has performed more than 20,000 sclerotherapy procedures for patients with varicose and spider veins.

Success Rates: The Section of Vascular Medicine at Cleveland Clinic is one of the most active Vascular Medicine programs in the United States. Our specialists treat patients with a wide variety of vascular problems, including all forms of arterial, venous, and lymphatic disorders, cardiovascular risk factor management, thrombotic disorders, hypercoagulable states and wound care. In addition, we have expertise on the use of the new oral anticoagulants. Cleveland Clinic has specialty clinics for patients with a number of disorders, including fibromuscular dysplasia, retrieval of Inferior vena cava filters, endovenous laser ablation (first nationally accredited academic practice), and lymphedema. Patients also benefit from programs designed as a result of the department’s close collaborations with Medical Genetics, Pulmonary Function lab and Physical Therapy. Success rates for specific procedures are available at

Education and Training: Dr. Bartholomew completed his undergraduate work at Central Michigan University, and received his medical degree from the Autonomous Universidad De Guadalajara, in Guadalajara, Jalisco, Mexico. He completed his internship and residency at Maryland General Hospital in Baltimore, where he was Chief Resident. Dr. Bartholomew was awarded a fellowship by the Johns Hopkins Hospital and appointed Senior Clinical Fellow in the Division of Hematology. While at Johns Hopkins, he received the William Bell Award for Patient Care.

Prior to joining the Cleveland Clinic in 1988, Dr. Bartholomew was the Assistant Director of Internal Medicine Education at St. Joseph Hospital at Michigan State University, where he was given the Instructor of the Year Award for the Family Practice Residency Program. He also served as Director of the Eastern Michigan Hemophilia Center.

Dr. Bartholomew is the Director of the Vascular Medicine Section’s anticoagulation clinic. In 2003, Dr. Bartholomew was part of the clinical faculty for the Joint Commission Resources, Inc., for the Joint Commission on Accreditation of Hospital Organizations (JCAHO). He has also been a member of the Deep Vein Thrombosis Steering Committee for the National Quality Forum, which sets the national standards for the care of patients with Deep Vein Thrombosis and Pulmonary Embolism. He currently serves as the Director of the Cleveland Clinic Health Systems efforts to prevent and treat deep vein thrombosis and pulmonary embolism. He has a joint clinic with Interventional Radiology to evaluate patients for retrieval of their inferior vena cava filters and is Co-Director of the Pulmonary Embolism Response Team.

Research, Publications and Speaking: Dr. Bartholomew has published numerous articles and abstracts in professional scientific journals, including the Annals of Internal Medicine, Journal of Thrombosis and Hemostasis, Journal of Thrombosis and Thrombolysis, Transfusion, Cardiovascular Surgery, Circulation, the Cleveland Clinic Journal of Medicine, Chest, Archives of Internal Medicine, American Journal of Cardiology, Journal of American College of Cardiology, Journal of Pediatrics, Vascular and Endovascular Surgery, and Vascular Medicine. His publications focus on topics related to smokeless tobacco and cardiovascular risk, peripheral artery disease, pulmonary embolism, and heparin-induced thrombocytopenia, and deep vein thrombosis, among others. He has written more than 45 chapters in medical textbooks related to atheromatous embolization, stasis leg ulcers, hypercoagulable states, heparin-induced thrombocytopenia, and peripheral arterial disease.

Dr. Bartholomew has spoken at many major national meetings, workshops, symposiums and conferences about the diagnosis and treatment of patients with deep vein and pulmonary embolism and peripheral arterial disease, and the diagnosis and management of patients with hypercoagulable states and heparin-induced thrombocytopenia, as well as patients with unusual vascular disorders and lymphedema and lipedema.

About Dr. Bartholomew: “I enjoy my field because many of the patients I treat have disorders that are not well known to other physicians. In that way, patients are extremely thankful that there are physicians that deal with these unusual and often complicated diseases. Many of our patients go from doctor to doctor before they find the right answer to their medical problems, and it is gratifying to let them know that someone understands what is wrong with them. In addition, I like the opportunity to use the newer anticoagulants to treat patients who have blood clots and to help advance the field of medicine related to those events.”

Leisure Activities: In his spare time, Dr. Bartholomew enjoys fishing, hiking, skiing, writing and reading.

Education & Fellowships

Fellowship - Johns Hopkins Hospital
Baltimore, MD USA
Residency - Maryland General Hospital
Internal Medicine
Baltimore, MD USA
Internship - Maryland General Hospital
Fifth Pathway
Baltimore, MD USA
Medical School - Universidad Autonoma De Guadalajara
Guadalajara, Jalisco Mexico
Undergraduate - Central Michigan University
Mt. Pleasant, MI USA


  • Internal Medicine

Specialty Interests

New oral anticoagulants, adverse effects of anticoagulants, heparin-induced thrombocytopenia, blood clots, hypercoagulable states (thrombophilia), deep vein thrombosis (DVT), pulmonary embolism, thrombosis in unusual locations, inferior vena cava filters, general vascular medicine, peripheral arterial disease, unusual vascular disorders including erythromelalgia, pernio, lymphedema and lipedema

Awards & Honors

  • 2014 Regional Top Doctor, Castle Connolly
  • Cleveland’s Best Doctors, Cleveland Magazine
  • Teacher of the Year, Cleveland Clinic Department of Vascular Medicine


  • Fellow, American College of Cardiology
  • Master, Society of Vascular Medicine
  • Fellow, International Academy of Clinical and Applied Thrombosis and Hemostasis
  • American Society of Hematology
  • Johns Hopkins Medical and Surgical Society
  • International Society of Thrombosis and Hemostasis



Treatment & Services

Specialty in Diseases and Conditions

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. The Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, the Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 6/3/2015, Dr. Bartholomew has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by the Cleveland Clinic. To learn more about the Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Bartholomew receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Daiichi Sankyo, Inc.

Donation of Financial Interest. Dr. Bartholomew has consulted for, received compensation for serving as a fiduciary from, or received royalties from the following companies but instructed them to donate all compensation to not-for-profit causes or to the Cleveland Clinic to support research and education:

  • Boehringer Ingelheim

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers’ discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Languages Spoken

  • English
  • Spanish

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